Flow microreactor synthesis in organo-fluorine chemistry
Organo-fluorine compounds are the substances of considerable interest in various industrial fields due to their unique physical and chemical properties. Despite increased demand in wide fields of science, synthesis of fluoro-organic compounds is still often faced with problems such as the difficulti...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Beilstein-Institut
2013-12-01
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| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.9.314 |
| _version_ | 1818955012518182912 |
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| author | Hideki Amii Aiichiro Nagaki Jun-ichi Yoshida |
| author_facet | Hideki Amii Aiichiro Nagaki Jun-ichi Yoshida |
| author_sort | Hideki Amii |
| collection | DOAJ |
| description | Organo-fluorine compounds are the substances of considerable interest in various industrial fields due to their unique physical and chemical properties. Despite increased demand in wide fields of science, synthesis of fluoro-organic compounds is still often faced with problems such as the difficulties in handling of fluorinating reagents and in controlling of chemical reactions. Recently, flow microreactor synthesis has emerged as a new methodology for producing chemical substances with high efficiency. This review outlines the successful examples of synthesis and reactions of fluorine-containing molecules by the use of flow microreactor systems to overcome long-standing problems in fluorine chemistry. |
| first_indexed | 2024-12-20T10:31:18Z |
| format | Article |
| id | doaj.art-3dc6e54f0c93420296d2077bebe3e7e0 |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-12-20T10:31:18Z |
| publishDate | 2013-12-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-3dc6e54f0c93420296d2077bebe3e7e02022-12-21T19:43:44ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972013-12-01912793280210.3762/bjoc.9.3141860-5397-9-314Flow microreactor synthesis in organo-fluorine chemistryHideki Amii0Aiichiro Nagaki1Jun-ichi Yoshida2Division of Molecular Science, Graduate School of Science and Technology, Gunma University, Tenjin-cho, Kiryu, Gunma 376-8515, JapanDepartment of Synthetic and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, JapanDepartment of Synthetic and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, JapanOrgano-fluorine compounds are the substances of considerable interest in various industrial fields due to their unique physical and chemical properties. Despite increased demand in wide fields of science, synthesis of fluoro-organic compounds is still often faced with problems such as the difficulties in handling of fluorinating reagents and in controlling of chemical reactions. Recently, flow microreactor synthesis has emerged as a new methodology for producing chemical substances with high efficiency. This review outlines the successful examples of synthesis and reactions of fluorine-containing molecules by the use of flow microreactor systems to overcome long-standing problems in fluorine chemistry.https://doi.org/10.3762/bjoc.9.314defluorinationfluorinefluorinationflow microreactororgano-fluorineperfluoroalkylation |
| spellingShingle | Hideki Amii Aiichiro Nagaki Jun-ichi Yoshida Flow microreactor synthesis in organo-fluorine chemistry Beilstein Journal of Organic Chemistry defluorination fluorine fluorination flow microreactor organo-fluorine perfluoroalkylation |
| title | Flow microreactor synthesis in organo-fluorine chemistry |
| title_full | Flow microreactor synthesis in organo-fluorine chemistry |
| title_fullStr | Flow microreactor synthesis in organo-fluorine chemistry |
| title_full_unstemmed | Flow microreactor synthesis in organo-fluorine chemistry |
| title_short | Flow microreactor synthesis in organo-fluorine chemistry |
| title_sort | flow microreactor synthesis in organo fluorine chemistry |
| topic | defluorination fluorine fluorination flow microreactor organo-fluorine perfluoroalkylation |
| url | https://doi.org/10.3762/bjoc.9.314 |
| work_keys_str_mv | AT hidekiamii flowmicroreactorsynthesisinorganofluorinechemistry AT aiichironagaki flowmicroreactorsynthesisinorganofluorinechemistry AT junichiyoshida flowmicroreactorsynthesisinorganofluorinechemistry |