Robust Control of Repeated Drug Administration with Variable Doses Based on Uncertain Mathematical Model

Robust Control of Repeated Drug Administration with Variable Doses Based on Uncertain Mathematical Model

The aim of this paper was to design a repeated drug administration strategy to reach and maintain the requested drug concentration in the body. Conservative designs require an exact knowledge of pharmacokinetic parameters, which is considered an unrealistic demand. The problem is usually resolved us...

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Bibliographic Details
Main Authors: Zuzana Vitková, Martin Dodek, Eva Miklovičová, Jarmila Pavlovičová, Andrej Babinec, Anton Vitko
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Bioengineering
Subjects:
pharmacokinetics
compartmental models
closed loop control
repeated drug administration
robust control
Online Access:https://www.mdpi.com/2306-5354/10/8/921

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