The Incidence of Perioperative Hypotension in Patients Undergoing Major Abdominal Surgery with the Use of Arterial Waveform Analysis and the Hypotension Prediction Index Hemodynamic Monitoring—A Retrospective Analysis

Intraoperative hypotension (IH) is common in patients receiving general anesthesia and can lead to serious complications such as kidney failure, myocardial injury and increased mortality. The Hypotension Prediction Index (HPI) algorithm is a machine learning system that analyzes the arterial pressur...

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Main Authors: Jakub Szrama, Agata Gradys, Tomasz Bartkowiak, Amadeusz Woźniak, Zuzanna Nowak, Krzysztof Zwoliński, Ashish Lohani, Natalia Jawień, Piotr Smuszkiewicz, Krzysztof Kusza
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Journal of Personalized Medicine
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Online Access:https://www.mdpi.com/2075-4426/14/2/174
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author Jakub Szrama
Agata Gradys
Tomasz Bartkowiak
Amadeusz Woźniak
Zuzanna Nowak
Krzysztof Zwoliński
Ashish Lohani
Natalia Jawień
Piotr Smuszkiewicz
Krzysztof Kusza
author_facet Jakub Szrama
Agata Gradys
Tomasz Bartkowiak
Amadeusz Woźniak
Zuzanna Nowak
Krzysztof Zwoliński
Ashish Lohani
Natalia Jawień
Piotr Smuszkiewicz
Krzysztof Kusza
author_sort Jakub Szrama
collection DOAJ
description Intraoperative hypotension (IH) is common in patients receiving general anesthesia and can lead to serious complications such as kidney failure, myocardial injury and increased mortality. The Hypotension Prediction Index (HPI) algorithm is a machine learning system that analyzes the arterial pressure waveform and alerts the clinician of an impending hypotension event. The purpose of the study was to compare the frequency of perioperative hypotension in patients undergoing major abdominal surgery with different types of hemodynamic monitoring. The study included 61 patients who were monitored with the arterial pressure-based cardiac output (APCO) technology (FloTrac group) and 62 patients with the Hypotension Prediction Index algorithm (HPI group). Our primary outcome was the time-weighted average (TWA) of hypotension below < 65 mmHg. The median TWA of hypotension in the FloTrac group was 0.31 mmHg versus 0.09 mmHg in the HPI group (<i>p</i> = 0.000009). In the FloTrac group, the average time of hypotension was 27.9 min vs. 8.1 min in the HPI group (<i>p</i> = 0.000023). By applying the HPI algorithm in addition to an arterial waveform analysis alone, we were able to significantly decrease the frequency and duration of perioperative hypotension events in patients who underwent major abdominal surgery.
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spelling doaj.art-3dcb07cefe0f49bfa9bbdadcc2b012a62024-02-23T15:23:46ZengMDPI AGJournal of Personalized Medicine2075-44262024-02-0114217410.3390/jpm14020174The Incidence of Perioperative Hypotension in Patients Undergoing Major Abdominal Surgery with the Use of Arterial Waveform Analysis and the Hypotension Prediction Index Hemodynamic Monitoring—A Retrospective AnalysisJakub Szrama0Agata Gradys1Tomasz Bartkowiak2Amadeusz Woźniak3Zuzanna Nowak4Krzysztof Zwoliński5Ashish Lohani6Natalia Jawień7Piotr Smuszkiewicz8Krzysztof Kusza9Department of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandDepartment of Anesthesiology, Intensive Therapy and Pain Management, Poznan University of Medical Sciences, 60-355 Poznan, PolandIntraoperative hypotension (IH) is common in patients receiving general anesthesia and can lead to serious complications such as kidney failure, myocardial injury and increased mortality. The Hypotension Prediction Index (HPI) algorithm is a machine learning system that analyzes the arterial pressure waveform and alerts the clinician of an impending hypotension event. The purpose of the study was to compare the frequency of perioperative hypotension in patients undergoing major abdominal surgery with different types of hemodynamic monitoring. The study included 61 patients who were monitored with the arterial pressure-based cardiac output (APCO) technology (FloTrac group) and 62 patients with the Hypotension Prediction Index algorithm (HPI group). Our primary outcome was the time-weighted average (TWA) of hypotension below < 65 mmHg. The median TWA of hypotension in the FloTrac group was 0.31 mmHg versus 0.09 mmHg in the HPI group (<i>p</i> = 0.000009). In the FloTrac group, the average time of hypotension was 27.9 min vs. 8.1 min in the HPI group (<i>p</i> = 0.000023). By applying the HPI algorithm in addition to an arterial waveform analysis alone, we were able to significantly decrease the frequency and duration of perioperative hypotension events in patients who underwent major abdominal surgery.https://www.mdpi.com/2075-4426/14/2/174perioperative hypotensionhemodynamic monitoringhypotension prediction indexarterial pressure-based cardiac output
spellingShingle Jakub Szrama
Agata Gradys
Tomasz Bartkowiak
Amadeusz Woźniak
Zuzanna Nowak
Krzysztof Zwoliński
Ashish Lohani
Natalia Jawień
Piotr Smuszkiewicz
Krzysztof Kusza
The Incidence of Perioperative Hypotension in Patients Undergoing Major Abdominal Surgery with the Use of Arterial Waveform Analysis and the Hypotension Prediction Index Hemodynamic Monitoring—A Retrospective Analysis
Journal of Personalized Medicine
perioperative hypotension
hemodynamic monitoring
hypotension prediction index
arterial pressure-based cardiac output
title The Incidence of Perioperative Hypotension in Patients Undergoing Major Abdominal Surgery with the Use of Arterial Waveform Analysis and the Hypotension Prediction Index Hemodynamic Monitoring—A Retrospective Analysis
title_full The Incidence of Perioperative Hypotension in Patients Undergoing Major Abdominal Surgery with the Use of Arterial Waveform Analysis and the Hypotension Prediction Index Hemodynamic Monitoring—A Retrospective Analysis
title_fullStr The Incidence of Perioperative Hypotension in Patients Undergoing Major Abdominal Surgery with the Use of Arterial Waveform Analysis and the Hypotension Prediction Index Hemodynamic Monitoring—A Retrospective Analysis
title_full_unstemmed The Incidence of Perioperative Hypotension in Patients Undergoing Major Abdominal Surgery with the Use of Arterial Waveform Analysis and the Hypotension Prediction Index Hemodynamic Monitoring—A Retrospective Analysis
title_short The Incidence of Perioperative Hypotension in Patients Undergoing Major Abdominal Surgery with the Use of Arterial Waveform Analysis and the Hypotension Prediction Index Hemodynamic Monitoring—A Retrospective Analysis
title_sort incidence of perioperative hypotension in patients undergoing major abdominal surgery with the use of arterial waveform analysis and the hypotension prediction index hemodynamic monitoring a retrospective analysis
topic perioperative hypotension
hemodynamic monitoring
hypotension prediction index
arterial pressure-based cardiac output
url https://www.mdpi.com/2075-4426/14/2/174
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