Sudden Increase of Antipsychotics and Induction of Deep Vein Thrombosis

Introduction: Antipsychotics (APs) can induce pathological blood clotting. Deep Vein Thrombosis (DVT) is a common type of Venous Thromboembolism (VTE) and a significant cause of morbidity and mortality worldwide. First or second generation APs have been specifically correlated with an increased risk...

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Main Authors: Arghavan Fariborzifar, Forouzan Elyasi, Marziyeh Azizi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2020-07-01
Series:Case Reports in Clinical Practice
Subjects:
Online Access:https://crcp.tums.ac.ir/index.php/crcp/article/view/299
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author Arghavan Fariborzifar
Forouzan Elyasi
Marziyeh Azizi
author_facet Arghavan Fariborzifar
Forouzan Elyasi
Marziyeh Azizi
author_sort Arghavan Fariborzifar
collection DOAJ
description Introduction: Antipsychotics (APs) can induce pathological blood clotting. Deep Vein Thrombosis (DVT) is a common type of Venous Thromboembolism (VTE) and a significant cause of morbidity and mortality worldwide. First or second generation APs have been specifically correlated with an increased risk of thromboembolism. Case presentation: We report a case of a bipolar female patient who developed DVT following an increase in her daily dose of APs (olanzapine and chlorpromazine). Conclusion: Physicians in other medical fields, including internal medicine and surgery, should be trained about the complication of DVT induced by APs.
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spelling doaj.art-3dd2efd2547346efb65c9efe164f72da2022-12-22T03:16:29ZengTehran University of Medical SciencesCase Reports in Clinical Practice2538-26832538-26912020-07-015110.18502/crcp.v5i1.3610Sudden Increase of Antipsychotics and Induction of Deep Vein ThrombosisArghavan Fariborzifar0Forouzan Elyasi1Marziyeh Azizi2Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.Department of Psychiatry, Psychiatry and Behavioral Sciences Research Center, Sexual and Reproductive Health Research Center, Iranian National Center for Addiction Studies, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.Ph.D. Student of Reproductive Health, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.Introduction: Antipsychotics (APs) can induce pathological blood clotting. Deep Vein Thrombosis (DVT) is a common type of Venous Thromboembolism (VTE) and a significant cause of morbidity and mortality worldwide. First or second generation APs have been specifically correlated with an increased risk of thromboembolism. Case presentation: We report a case of a bipolar female patient who developed DVT following an increase in her daily dose of APs (olanzapine and chlorpromazine). Conclusion: Physicians in other medical fields, including internal medicine and surgery, should be trained about the complication of DVT induced by APs.https://crcp.tums.ac.ir/index.php/crcp/article/view/299AntipsychoticsOlanzapineDeep vein thrombosisVenous thromboembolism
spellingShingle Arghavan Fariborzifar
Forouzan Elyasi
Marziyeh Azizi
Sudden Increase of Antipsychotics and Induction of Deep Vein Thrombosis
Case Reports in Clinical Practice
Antipsychotics
Olanzapine
Deep vein thrombosis
Venous thromboembolism
title Sudden Increase of Antipsychotics and Induction of Deep Vein Thrombosis
title_full Sudden Increase of Antipsychotics and Induction of Deep Vein Thrombosis
title_fullStr Sudden Increase of Antipsychotics and Induction of Deep Vein Thrombosis
title_full_unstemmed Sudden Increase of Antipsychotics and Induction of Deep Vein Thrombosis
title_short Sudden Increase of Antipsychotics and Induction of Deep Vein Thrombosis
title_sort sudden increase of antipsychotics and induction of deep vein thrombosis
topic Antipsychotics
Olanzapine
Deep vein thrombosis
Venous thromboembolism
url https://crcp.tums.ac.ir/index.php/crcp/article/view/299
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AT marziyehazizi suddenincreaseofantipsychoticsandinductionofdeepveinthrombosis