Hypoxia/reoxygenation-induced myocardial lesions in newborn piglets are related to interindividual variability and not to oxygen concentration

Hypoxia/reoxygenation-induced myocardial lesions in newborn piglets are related to interindividual variability and not to oxygen concentration

OBJECTIVE: Evaluation of myocardial histological changes in an experimental animal model of neonatal hypoxiareoxygenation. METHODS: Normocapnic hypoxia was induced in 40 male Landrace/Large White piglets. Reoxygenation was initiated when the animals developed bradycardia (HR <60 beats/min) or sev...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Armando Faa, Nicoletta Iacovidou, Theodoros Xanthos, Annalisa Locci, Pietro Pampaloni, Filippia Aroni, Apostolos Papalois, Gavino Faa, Vassilios Fanos
Natura:	Articolo
Lingua:	English
Pubblicazione:	Elsevier España 2012-01-01
Serie:	Clinics
Soggetti:	Cardiomyocyte Coagulative Necrosis Hypoxia Reoxygenation Newborn Piglet
Accesso online:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322012000500016

Documenti analoghi

PDRPS7 protects cardiac cells from hypoxia/reoxygenation injury through inactivation of JNKs
di: Yulian Duan, et al.
Pubblicazione: (2020-04-01)

Propofol reduces anoxia-reoxygenation-induced injury of cardiomyocytes
di: CHEN Si, YANG Fu-guo, PENG Hong-jun, CAO Wei-le, WANG Zhen-yu
Pubblicazione: (2022-04-01)

Hydrogen Sulfide Attenuates Myocardial Hypoxia-Reoxygenation Injury by Inhibiting Autophagy via mTOR Activation
di: Jian Xiao, et al.
Pubblicazione: (2015-12-01)

Herbal formula Xinshuitong capsule exerts its cardioprotective effects via mitochondria in the hypoxia-reoxygenated human cardiomyocytes
di: Chunjiang Tan, et al.
Pubblicazione: (2018-05-01)

Inflammation and oxidative stress biomarkers in neonatal brain hypoxia and prediction of adverse neurological outcome: a review
di: Marianna Varsami, et al.
Pubblicazione: (2013-07-01)

Sevoflurane postconditioning attenuates cardiomyocyte hypoxia/reoxygenation injury via restoring mitochondrial morphology
di: Jin Yu, et al.
Pubblicazione: (2016-11-01)

The effect of erythropoietin on calcium levels during hypoxia reoxygenation injury in rats
di: Constantinos Tsompos, et al.
Pubblicazione: (2016-04-01)

The Acute Effect of Erythropoietin on Mean Platelet Volume Levels during Hypoxia Reoxygenation Injury in Rats
di: Constantinos Tsompos, et al.
Pubblicazione: (2016-12-01)

Is the quickness of resuscitation after hypoxia influenced by the oxygen concentration? Metabolomics in piglets resuscitated with different oxygen concentrations
di: Federica Murgia, et al.
Pubblicazione: (2013-10-01)

Ginsenoside Re Treatment Attenuates Myocardial Hypoxia/Reoxygenation Injury by Inhibiting HIF-1α Ubiquitination
di: Huiyuan Sun, et al.
Pubblicazione: (2020-09-01)

Carvedilol Confers Ferroptosis Resistance in HL-1 Cells by Upregulating GPX4, FTH1, and FTL1 and Inducing Metabolic Remodeling Under Hypoxia/Reoxygenation
di: Yi-Chin Li, et al.
Pubblicazione: (2024-12-01)

Inhibition of mir-155-5p alleviates cardiomyocyte pyroptosis induced by hypoxia/reoxygenation via targeting SIRT1-mediated activation of the NLRP3 inflammasome
di: Qiuyu Lu, et al.
Pubblicazione: (2025-02-01)

miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner
di: Gurdeep Marwarha, et al.
Pubblicazione: (2021-12-01)

Stachydrine ameliorates hypoxia reoxygenation injury of cardiomyocyte via enhancing SIRT1-Nrf2 pathway
di: Xi Zhu, et al.
Pubblicazione: (2023-09-01)

Co-loading antioxidant N-acetylcysteine attenuates cytotoxicity of iron oxide nanoparticles in hypoxia/reoxygenation cardiomyocytes
di: Shen Y, et al.
Pubblicazione: (2019-08-01)

Geniposide Prevents Hypoxia/Reoxygenation-Induced Apoptosis in H9c2 Cells: Improvement of Mitochondrial Dysfunction and Activation of GLP-1R and the PI3K/AKT Signaling Pathway
di: You-Qin Jiang, et al.
Pubblicazione: (2016-07-01)

Diazoxide Post-conditioning Activates the HIF-1/HRE Pathway to Induce Myocardial Protection in Hypoxic/Reoxygenated Cardiomyocytes
di: Xi-Yuan Chen, et al.
Pubblicazione: (2021-12-01)

Corrigendum: Diazoxide post-conditioning activates the HIF-1/HRE pathway to induce myocardial protection in hypoxic/reoxygenated cardiomyocytes
di: Xi-Yuan Chen, et al.
Pubblicazione: (2023-09-01)

Icariin inhibits hypoxia/reoxygenation‐induced ferroptosis of cardiomyocytes via regulation of the Nrf2/HO‐1 signaling pathway
di: Xiu‐Juan Liu, et al.
Pubblicazione: (2021-11-01)

The Acute Effect of the Antioxidant Drug U-74389G on Red Blood Cell Distribution Width Levels During Hypoxia Reoxygenation Injury in Rats
di: Tsompos Constantinos, et al.
Pubblicazione: (2015-12-01)

METTL14-mediated N6-methyladenosine modification induces the ferroptosis of hypoxia/reoxygenation-induced cardiomyocytes
di: Chunyu Zhao, et al.
Pubblicazione: (2024-04-01)

Assessing the regulatory impact of mi RNA-335–5p on hypoxia reoxygenation-induced cardiomyocytes in neonatal rats
di: Jian-Rong Xu, et al.
Pubblicazione: (2024-10-01)

The acute effect of the antioxidant drug “U-74389G” on red blood cells levels during hypoxia reoxygenation injury in rats
di: C Tsompos, et al.
Pubblicazione: (2014-01-01)

Photoacoustic lifetime oxygen imaging of radiotherapy-induced tumor reoxygenation In Vivo
di: Jeff Folz, et al.
Pubblicazione: (2024-06-01)

Decrease in Cerebral Blood Flow after Reoxygenation Is Associated with Neurological Syndrome Sequelae and Blood Pressure
di: Yanqiu Liu, et al.
Pubblicazione: (2023-11-01)

Shikonin attenuates hypoxia-reoxygenation-induced injury of cardiomyocyte cell line H9c2
di: LIU Ming, YANG Chen-li, MENG Qing-xin
Pubblicazione: (2020-03-01)

Perinatal cardiac failure from the eyes of the pathologist
di: Armando Faa, et al.
Pubblicazione: (2014-10-01)

In Vitro Modeling of Reoxygenation Effects on mRNA and Protein Levels in Hypoxic Tumor Cells upon Entry into the Bloodstream
di: Kai Bartkowiak, et al.
Pubblicazione: (2020-05-01)

Metabolomic and Lipidomic Analysis of the Colorectal Adenocarcinoma Cell Line HT29 in Hypoxia and Reoxygenation
di: Juan Carlos Alarcon Barrera, et al.
Pubblicazione: (2023-07-01)

Renal endogenous stem cells: a new source for regenerative medicine in preterms?
di: Gavino Faa, et al.
Pubblicazione: (2015-10-01)

Resveratrol relieves hypoxia-reoxygenation-induced mitophagy in TCMK1 cells
di: JIANG Luo-jia, XU Hai-bo
Pubblicazione: (2022-11-01)

Hyaline membrane disease (HMD): the role of the perinatal pathologist
di: Giorgia Locci, et al.
Pubblicazione: (2014-10-01)

Overcoming Hypoxia-Induced Drug Resistance via Promotion of Drug Uptake and Reoxygenation by Acousto–Mechanical Oxygen Delivery
di: Yi-Ju Ho, et al.
Pubblicazione: (2022-04-01)

Upregulation of cardiac NO/NOS system during short-term hypoxia and the subsequent reoxygenation period
di: A. Rus, et al.
Pubblicazione: (2011-05-01)

The next ten years in neonatology: new directions in research
di: Vassilios Fanos, et al.
Pubblicazione: (2014-10-01)

Dual-Tracer Assessment of Dynamic Changes in Reoxygenation and Proliferation Decrease During Fractionated Radiotherapy in Murine Tumors
di: Wenjing Yu, et al.
Pubblicazione: (2020-07-01)

The therapeutic effect of controlled reoxygenation on chronic hypoxia-associated brain injury
di: Zhenzhen Tu, et al.
Pubblicazione: (2019-12-01)

Long-term hypoxia and reoxygenation induced oxidative stress lead to immunosuppression and apoptosis in golden pompano (Trachinotus blochii)
di: Yue Gu, et al.
Pubblicazione: (2023-07-01)

Reoxygenation Reverses Hypoxic Pulmonary Arterial Remodeling by Inducing Smooth Muscle Cell Apoptosis via Reactive Oxygen Species–Mediated Mitochondrial Dysfunction
di: Jian Chen, et al.
Pubblicazione: (2017-11-01)

Acetylcholine Mediates AMPK-Dependent Autophagic Cytoprotection in H9c2 Cells During Hypoxia/Reoxygenation Injury
di: Mei Zhao, et al.
Pubblicazione: (2013-09-01)