Mn-mediated sequential three-component domino Knoevenagel/cyclization/Michael addition/oxidative cyclization reaction towards annulated imidazo[1,2-a]pyridines

Mn-mediated sequential three-component domino Knoevenagel/cyclization/Michael addition/oxidative cyclization reaction towards annulated imidazo[1,2-a]pyridines

The sequential three-component reaction between o-hydroxybenzaldehydes, N-(cyanomethyl)pyridinium salts and a nucleophile towards substituted chromenoimidazopyridines under oxidative conditions has been developed. The employment of Mn(OAc)3·2H2O or KMnO4 as stoichiometric oxidants allowed the use of...

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Bibliographic Details
Main Authors:	Olga A. Storozhenko, Alexey A. Festa, Delphine R. Bella Ndoutoume, Alexander V. Aksenov, Alexey V. Varlamov, Leonid G. Voskressensky
Format:	Article
Language:	English
Published:	Beilstein-Institut 2018-12-01
Series:	Beilstein Journal of Organic Chemistry
Subjects:	2-aminochromene domino reaction imidazo[1,2-a]pyridine 2-iminochromene Michael addition multicomponent reaction oxidation pyridine amination
Online Access:	https://doi.org/10.3762/bjoc.14.287

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