[3+2] Cycloaddition Reaction for the Stereoselective Synthesis of a New Spirooxindole Compound Grafted Imidazo[2,1-<em>b</em>]thiazole Scaffold: Crystal Structure and Computational Study

[3+2] Cycloaddition Reaction for the Stereoselective Synthesis of a New Spirooxindole Compound Grafted Imidazo[2,1-<em>b</em>]thiazole Scaffold: Crystal Structure and Computational Study

A new spirooxindole hybrid engrafted imidazo[2,1-<i>b</i>]thiazole core structure was designed and achieved via [3+2] cycloaddition reaction approach. One multi-component reaction between the ethylene derivative based imidazo[2,1-<i>b</i>]thiazole scaffold with 6-Cl-isatin an...

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Bibliographic Details
Main Authors: Mezna Saleh Altowyan, Saied M. Soliman, Matti Haukka, Nora Hamad Al-Shaalan, Aminah A. Alkharboush, Assem Barakat
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Crystals
Subjects:
spirooxindole
imidazo[2,1-<i>b</i>]thiazole
azomethine ylide
[3+2] cycloaddition (32CA) reaction
Online Access:https://www.mdpi.com/2073-4352/12/1/5

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