A case report of hypertensive bleed presenting with pathological laughter: Focus on neurobiological correlates and pharmacological management

Pathological laughter and crying are episodes of either laughter or crying, which is intense and uncontrollable, usually lasting for brief periods and occurring in paroxysms. In the literature, pathological laughing and crying, emotionalism, pseudo-bulbar affect are synonymously used. Favorable evid...

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Bibliographic Details
Main Authors: Sujita Kumar Kar, Akhila Kumar Panda
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Geriatric Mental Health
Subjects:
Online Access:http://www.jgmh.org/article.asp?issn=2348-9995;year=2015;volume=2;issue=1;spage=46;epage=49;aulast=Kar
Description
Summary:Pathological laughter and crying are episodes of either laughter or crying, which is intense and uncontrollable, usually lasting for brief periods and occurring in paroxysms. In the literature, pathological laughing and crying, emotionalism, pseudo-bulbar affect are synonymously used. Favorable evidences exist with regard to the use of antidepressants, mood stabilizers, and anti-glutaminergic agents for the management of pathological laughter and crying. In this case report, we highlight the clinical presentation of hypertensive bleed in the form of pathological laughter and its management with selective serotonin reuptake inhibitor - sertraline along with literature review regarding its neurobiological basis and pharmacological management.
ISSN:2348-9995
2395-3322