Analytical validation of the Percepta genomic sequencing classifier; an RNA next generation sequencing assay for the assessment of Lung Cancer risk of suspicious pulmonary nodules

Analytical validation of the Percepta genomic sequencing classifier; an RNA next generation sequencing assay for the assessment of Lung Cancer risk of suspicious pulmonary nodules

Abstract Background Bronchoscopy is a common procedure used for evaluation of suspicious lung nodules, but the low diagnostic sensitivity of bronchoscopy often results in inconclusive results and delays in treatment. Percepta Genomic Sequencing Classifier (GSC) was developed to assist with patient m...

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Bibliographic Details
Main Authors: Marla K. Johnson, Shuyang Wu, Daniel G. Pankratz, Grazyna Fedorowicz, Jessica Anderson, Jie Ding, Mei Wong, Manqiu Cao, Joshua Babiarz, Lori Lofaro, P. Sean Walsh, Giulia C. Kennedy, Jing Huang
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
Percepta
Genomic sequencing classifier
Molecular diagnostic
Lung lesion
Bronchial brushing specimen
Analytical validation
Online Access:https://doi.org/10.1186/s12885-021-08130-x

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