Brain Metastases from Non-small-cell Lung Carcinoma – CyberKnife Re-irradiation after Gamma Knife Radiosurgery

Lung cancer is the most common neoplasia and the most common cause of cancer mortality. The condition is usually diagnosed at a locally advanced or metastatic stage, which is a bad prognostic factor. Around 40% of all oncology patients with brain metastases have lung cancer.Modern linear accelerator...

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Main Author: Veselin Popov
Format: Article
Language:English
Published: Pensoft Publishers 2020-12-01
Series:Folia Medica
Subjects:
Online Access:https://foliamedica.bg/article/52182/download/pdf/
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author Veselin Popov
author_facet Veselin Popov
author_sort Veselin Popov
collection DOAJ
description Lung cancer is the most common neoplasia and the most common cause of cancer mortality. The condition is usually diagnosed at a locally advanced or metastatic stage, which is a bad prognostic factor. Around 40% of all oncology patients with brain metastases have lung cancer.Modern linear accelerators allow clinicians to perform radiosurgery and deliver a high radiation dose to low volume with a high dose gradient. Herein we present a 55-year-old male patient who received radiosurgery four times over three years – two times with Gamma Knife and two times with CyberKnife. Re-irradiation gives the opportunity to treat a local progression of a metastasis, which already has been irradiated. A series of control brain magnetic resonance imaging confirmed a good local control of treated lesions with no necrosis in surrounding healthy tissue or significant oedema. The neurological symptoms were completely controlled and the quality of life of the patient improved considerably. Radiosurgery is a prevalent, non-invasive, painless method of treatment with proven clinical results. It may be reused as long as it has clinical benefits to the patient.
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spelling doaj.art-3de8efd7f4cc4ab1a8c50bcfaefa22902022-12-21T17:23:46ZengPensoft PublishersFolia Medica1314-21432020-12-0162485686010.3897/folmed.62.e5218252182Brain Metastases from Non-small-cell Lung Carcinoma – CyberKnife Re-irradiation after Gamma Knife RadiosurgeryVeselin Popov0Medical University of PlovdivLung cancer is the most common neoplasia and the most common cause of cancer mortality. The condition is usually diagnosed at a locally advanced or metastatic stage, which is a bad prognostic factor. Around 40% of all oncology patients with brain metastases have lung cancer.Modern linear accelerators allow clinicians to perform radiosurgery and deliver a high radiation dose to low volume with a high dose gradient. Herein we present a 55-year-old male patient who received radiosurgery four times over three years – two times with Gamma Knife and two times with CyberKnife. Re-irradiation gives the opportunity to treat a local progression of a metastasis, which already has been irradiated. A series of control brain magnetic resonance imaging confirmed a good local control of treated lesions with no necrosis in surrounding healthy tissue or significant oedema. The neurological symptoms were completely controlled and the quality of life of the patient improved considerably. Radiosurgery is a prevalent, non-invasive, painless method of treatment with proven clinical results. It may be reused as long as it has clinical benefits to the patient.https://foliamedica.bg/article/52182/download/pdf/brain metastasesCyberKnifegamma kniferadiosu
spellingShingle Veselin Popov
Brain Metastases from Non-small-cell Lung Carcinoma – CyberKnife Re-irradiation after Gamma Knife Radiosurgery
Folia Medica
brain metastases
CyberKnife
gamma knife
radiosu
title Brain Metastases from Non-small-cell Lung Carcinoma – CyberKnife Re-irradiation after Gamma Knife Radiosurgery
title_full Brain Metastases from Non-small-cell Lung Carcinoma – CyberKnife Re-irradiation after Gamma Knife Radiosurgery
title_fullStr Brain Metastases from Non-small-cell Lung Carcinoma – CyberKnife Re-irradiation after Gamma Knife Radiosurgery
title_full_unstemmed Brain Metastases from Non-small-cell Lung Carcinoma – CyberKnife Re-irradiation after Gamma Knife Radiosurgery
title_short Brain Metastases from Non-small-cell Lung Carcinoma – CyberKnife Re-irradiation after Gamma Knife Radiosurgery
title_sort brain metastases from non small cell lung carcinoma amp ndash cyberknife re irradiation after gamma knife radiosurgery
topic brain metastases
CyberKnife
gamma knife
radiosu
url https://foliamedica.bg/article/52182/download/pdf/
work_keys_str_mv AT veselinpopov brainmetastasesfromnonsmallcelllungcarcinomaampndashcyberknifereirradiationaftergammakniferadiosurgery