Graphene Oxide Nanostructures as Nanoplatforms for Delivering Natural Therapeutic Agents: Applications in Cancer Treatment, Bacterial Infections, and Bone Regeneration Medicine

Graphene, fullerenes, diamond, carbon nanotubes, and carbon dots are just a few of the carbon-based nanomaterials that have gained enormous popularity in a variety of scientific disciplines and industrial uses. As a two-dimensional material in the creation of therapeutic delivery systems for many il...

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Main Authors: Khaled AbouAitah, Farzaneh Sabbagh, Beom Soo Kim
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/13/19/2666
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author Khaled AbouAitah
Farzaneh Sabbagh
Beom Soo Kim
author_facet Khaled AbouAitah
Farzaneh Sabbagh
Beom Soo Kim
author_sort Khaled AbouAitah
collection DOAJ
description Graphene, fullerenes, diamond, carbon nanotubes, and carbon dots are just a few of the carbon-based nanomaterials that have gained enormous popularity in a variety of scientific disciplines and industrial uses. As a two-dimensional material in the creation of therapeutic delivery systems for many illnesses, nanosized graphene oxide (NGO) is now garnering a large amount of attention among these materials. In addition to other benefits, NGO functions as a drug nanocarrier with remarkable biocompatibility, high pharmaceutical loading capacity, controlled drug release capability, biological imaging efficiency, multifunctional nanoplatform properties, and the power to increase the therapeutic efficacy of loaded agents. Thus, NGO is a perfect nanoplatform for the development of drug delivery systems (DDSs) to both detect and treat a variety of ailments. This review article’s main focus is on investigating surface functionality, drug-loading methods, and drug release patterns designed particularly for smart delivery systems. The paper also examines the relevance of using NGOs to build DDSs and considers prospective uses in the treatment of diseases including cancer, infection by bacteria, and bone regeneration medicine. These factors cover the use of naturally occurring medicinal substances produced from plant-based sources.
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spelling doaj.art-3debd577982744d3969de94f17012e9e2023-11-19T14:49:07ZengMDPI AGNanomaterials2079-49912023-09-011319266610.3390/nano13192666Graphene Oxide Nanostructures as Nanoplatforms for Delivering Natural Therapeutic Agents: Applications in Cancer Treatment, Bacterial Infections, and Bone Regeneration MedicineKhaled AbouAitah0Farzaneh Sabbagh1Beom Soo Kim2Department of Chemical Engineering, Chungbuk National University, Cheongju 28644, Republic of KoreaDepartment of Chemical Engineering, Chungbuk National University, Cheongju 28644, Republic of KoreaDepartment of Chemical Engineering, Chungbuk National University, Cheongju 28644, Republic of KoreaGraphene, fullerenes, diamond, carbon nanotubes, and carbon dots are just a few of the carbon-based nanomaterials that have gained enormous popularity in a variety of scientific disciplines and industrial uses. As a two-dimensional material in the creation of therapeutic delivery systems for many illnesses, nanosized graphene oxide (NGO) is now garnering a large amount of attention among these materials. In addition to other benefits, NGO functions as a drug nanocarrier with remarkable biocompatibility, high pharmaceutical loading capacity, controlled drug release capability, biological imaging efficiency, multifunctional nanoplatform properties, and the power to increase the therapeutic efficacy of loaded agents. Thus, NGO is a perfect nanoplatform for the development of drug delivery systems (DDSs) to both detect and treat a variety of ailments. This review article’s main focus is on investigating surface functionality, drug-loading methods, and drug release patterns designed particularly for smart delivery systems. The paper also examines the relevance of using NGOs to build DDSs and considers prospective uses in the treatment of diseases including cancer, infection by bacteria, and bone regeneration medicine. These factors cover the use of naturally occurring medicinal substances produced from plant-based sources.https://www.mdpi.com/2079-4991/13/19/2666nanographene oxidecancer therapybacterial infectionsbone regeneration medicinenanoformulationsdelivery systems
spellingShingle Khaled AbouAitah
Farzaneh Sabbagh
Beom Soo Kim
Graphene Oxide Nanostructures as Nanoplatforms for Delivering Natural Therapeutic Agents: Applications in Cancer Treatment, Bacterial Infections, and Bone Regeneration Medicine
Nanomaterials
nanographene oxide
cancer therapy
bacterial infections
bone regeneration medicine
nanoformulations
delivery systems
title Graphene Oxide Nanostructures as Nanoplatforms for Delivering Natural Therapeutic Agents: Applications in Cancer Treatment, Bacterial Infections, and Bone Regeneration Medicine
title_full Graphene Oxide Nanostructures as Nanoplatforms for Delivering Natural Therapeutic Agents: Applications in Cancer Treatment, Bacterial Infections, and Bone Regeneration Medicine
title_fullStr Graphene Oxide Nanostructures as Nanoplatforms for Delivering Natural Therapeutic Agents: Applications in Cancer Treatment, Bacterial Infections, and Bone Regeneration Medicine
title_full_unstemmed Graphene Oxide Nanostructures as Nanoplatforms for Delivering Natural Therapeutic Agents: Applications in Cancer Treatment, Bacterial Infections, and Bone Regeneration Medicine
title_short Graphene Oxide Nanostructures as Nanoplatforms for Delivering Natural Therapeutic Agents: Applications in Cancer Treatment, Bacterial Infections, and Bone Regeneration Medicine
title_sort graphene oxide nanostructures as nanoplatforms for delivering natural therapeutic agents applications in cancer treatment bacterial infections and bone regeneration medicine
topic nanographene oxide
cancer therapy
bacterial infections
bone regeneration medicine
nanoformulations
delivery systems
url https://www.mdpi.com/2079-4991/13/19/2666
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AT farzanehsabbagh grapheneoxidenanostructuresasnanoplatformsfordeliveringnaturaltherapeuticagentsapplicationsincancertreatmentbacterialinfectionsandboneregenerationmedicine
AT beomsookim grapheneoxidenanostructuresasnanoplatformsfordeliveringnaturaltherapeuticagentsapplicationsincancertreatmentbacterialinfectionsandboneregenerationmedicine