A Microfluidic Device Based on Standing Surface Acoustic Waves for Sorting and Trapping Microparticles

Microfluidic devices can provide innovative means to handle and control the transport of (bio)particles within a fluid flow. The advantage of microscale devices is that different components can be integrated in a single chip at low cost, with a negligible power consumption, compared to alternative s...

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Main Authors: Gianluca Mezzanzanica, Luigi Agazzi, Martina Siena, Olivier Français, Stefano Mariani
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Engineering Proceedings
Subjects:
Online Access:https://www.mdpi.com/2673-4591/27/1/28
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author Gianluca Mezzanzanica
Luigi Agazzi
Martina Siena
Olivier Français
Stefano Mariani
author_facet Gianluca Mezzanzanica
Luigi Agazzi
Martina Siena
Olivier Français
Stefano Mariani
author_sort Gianluca Mezzanzanica
collection DOAJ
description Microfluidic devices can provide innovative means to handle and control the transport of (bio)particles within a fluid flow. The advantage of microscale devices is that different components can be integrated in a single chip at low cost, with a negligible power consumption, compared to alternative solutions. In this work, a numerical investigation is developed on the use of standing surface acoustic waves (SAWs) generated within a microfluidic channel in order to manipulate microparticles. Far-field waves are generated via inter-digital transducers (IDTs), travel on the surface of a piezoelectric substrate and finally interfere in the channel, giving rise to a standing wave solution in terms of acoustic pressure. Results are reported for different geometries of the channel, to define the sensitivity of the acoustic pressure field to the relevant geometric features of the channel. This investigation shows how the acoustic radiation and drag forces interact with each other to move and focus the particles, possibly leading to a separation of heterogeneous ones, and generally provide a way to manipulate them at a small scale.
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spelling doaj.art-3debd83826044feab2b9ca1e82a187572023-11-17T10:54:41ZengMDPI AGEngineering Proceedings2673-45912022-11-012712810.3390/ecsa-9-13362A Microfluidic Device Based on Standing Surface Acoustic Waves for Sorting and Trapping MicroparticlesGianluca Mezzanzanica0Luigi Agazzi1Martina Siena2Olivier Français3Stefano Mariani4Department of Civil and Environmental Engineering, Politecnico di Milano, 20133 Milano, ItalyDepartment of Civil and Environmental Engineering, Politecnico di Milano, 20133 Milano, ItalyDepartment of Civil and Environmental Engineering, Politecnico di Milano, 20133 Milano, ItalyESYCOM Lab, Université Gustave Eiffel, CNRS, F-77454 Marne-la-Vallée, FranceDepartment of Civil and Environmental Engineering, Politecnico di Milano, 20133 Milano, ItalyMicrofluidic devices can provide innovative means to handle and control the transport of (bio)particles within a fluid flow. The advantage of microscale devices is that different components can be integrated in a single chip at low cost, with a negligible power consumption, compared to alternative solutions. In this work, a numerical investigation is developed on the use of standing surface acoustic waves (SAWs) generated within a microfluidic channel in order to manipulate microparticles. Far-field waves are generated via inter-digital transducers (IDTs), travel on the surface of a piezoelectric substrate and finally interfere in the channel, giving rise to a standing wave solution in terms of acoustic pressure. Results are reported for different geometries of the channel, to define the sensitivity of the acoustic pressure field to the relevant geometric features of the channel. This investigation shows how the acoustic radiation and drag forces interact with each other to move and focus the particles, possibly leading to a separation of heterogeneous ones, and generally provide a way to manipulate them at a small scale.https://www.mdpi.com/2673-4591/27/1/28microfluidicsacoustophoresissurface acoustic wavesinter-digital transducersparticle manipulation
spellingShingle Gianluca Mezzanzanica
Luigi Agazzi
Martina Siena
Olivier Français
Stefano Mariani
A Microfluidic Device Based on Standing Surface Acoustic Waves for Sorting and Trapping Microparticles
Engineering Proceedings
microfluidics
acoustophoresis
surface acoustic waves
inter-digital transducers
particle manipulation
title A Microfluidic Device Based on Standing Surface Acoustic Waves for Sorting and Trapping Microparticles
title_full A Microfluidic Device Based on Standing Surface Acoustic Waves for Sorting and Trapping Microparticles
title_fullStr A Microfluidic Device Based on Standing Surface Acoustic Waves for Sorting and Trapping Microparticles
title_full_unstemmed A Microfluidic Device Based on Standing Surface Acoustic Waves for Sorting and Trapping Microparticles
title_short A Microfluidic Device Based on Standing Surface Acoustic Waves for Sorting and Trapping Microparticles
title_sort microfluidic device based on standing surface acoustic waves for sorting and trapping microparticles
topic microfluidics
acoustophoresis
surface acoustic waves
inter-digital transducers
particle manipulation
url https://www.mdpi.com/2673-4591/27/1/28
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