FGL1-LAG3 axis impairs IL-10-Producing regulatory T cells associated with Systemic lupus erythematosus disease activity

FGL1-LAG3 axis impairs IL-10-Producing regulatory T cells associated with Systemic lupus erythematosus disease activity

Background: Systemic Lupus Erythematosus (SLE) is a prototypic autoimmune disease, which is accompanied by liver damage. However, it remains unknown whether liver damage is associated with SLE progression. Method: ology: HepG2 and L-02 cells were stimulated with cytokines, and FGL1 mRNA and protein...

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Bibliographic Details
Main Authors: Kang Chen, Xingyu Li, Yuqi Shang, Daxiang Chen, Siying Qu, Jinxian Shu, Mei Zhang, Zhiying Wang, Jinmei Huang, Minhao Wu, Siqi Ming, Yongjian Wu
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Heliyon
Subjects:
Systemic lupus erythematosus
Regulatory T cell
Lymphocyte-activation protein 3
Fibrinogen-like protein 1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023080143

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http://www.sciencedirect.com/science/article/pii/S2405844023080143

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