In Vitro Toxic Effects of Puff Adder (Bitis arietans) Venom, and Their Neutralization by Antivenom

In Vitro Toxic Effects of Puff Adder (Bitis arietans) Venom, and Their Neutralization by Antivenom

This study investigated the in vitro toxic effects of Bitis arietans venom and the ability of antivenom produced by the South African Institute of Medical Research (SAIMR) to neutralize these effects. The venom (50 µg/mL) reduced nerve-mediated twitches of the chick biventer muscle to 19% ± 2% of in...

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Bibliographic Details
Main Authors: Steven Fernandez, Wayne Hodgson, Janeyuth Chaisakul, Rachelle Kornhauser, Nicki Konstantakopoulos, Alexander Ian Smith, Sanjaya Kuruppu
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Toxins
Subjects:
antivenom
Bitis arietans
neurotoxicity
myotoxicity
cytotoxicity
procoagulant
Online Access:http://www.mdpi.com/2072-6651/6/5/1586

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