Endovascular treatment for distal basilar artery occlusion stroke
BackgroundThis study aimed to investigate the clinical outcomes of endovascular treatment (EVT) for distal basilar artery occlusion (BAO) and compare them with the outcomes of standard medical treatment (SMT) in daily clinical practice.MethodsPatients with distal BAO enrolled in the BASILAR study fr...
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| Format: | Article |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.931507/full |
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| author | Jiaxing Song Zhou Yu Jian Wang Xiaojun Luo Jie Du Zhengxuan Tian Shunyu Yang Weihua Xie Yuqi Peng Jinlin Mu Wenjie Zi Shuchun Huang Mei Yang |
| author_facet | Jiaxing Song Zhou Yu Jian Wang Xiaojun Luo Jie Du Zhengxuan Tian Shunyu Yang Weihua Xie Yuqi Peng Jinlin Mu Wenjie Zi Shuchun Huang Mei Yang |
| author_sort | Jiaxing Song |
| collection | DOAJ |
| description | BackgroundThis study aimed to investigate the clinical outcomes of endovascular treatment (EVT) for distal basilar artery occlusion (BAO) and compare them with the outcomes of standard medical treatment (SMT) in daily clinical practice.MethodsPatients with distal BAO enrolled in the BASILAR study from January 2014 to May 2019 were included. Differences in clinical outcomes were analyzed using Pearson's chi-square test and multivariable logistic regression. Clinical outcomes were evaluated using the modified Rankin Scale (mRS) score at 90 days, the mortality at 90 days, and the occurrence of symptomatic intracranial hemorrhage within 48 h.ResultsAmong the 267 patients with distal BAO (222 patients in the EVT group and 45 patients in the SMT group), compared with the SMT group, the EVT group was associated with a favorable outcome (mRS 0–3; 40.1 vs. 15.6%; aOR 5.44; 95% CI, 1.68–17.66; P = 0.005) and decreased mortality (44.6 vs. 71.1%, aOR 0.32, 95% CI, 0.13–0.77; P = 0.012). In the EVT group, multivariable analysis showed that the initial National Institutes of Health Stroke Scale (NIHSS) score and posterior circulation-Alberta Stroke Program Early CT Score (pc-ASPECTS) were associated with favorable functional outcomes and mortality.ConclusionOur study suggests that, compared with SMT, EVT is technically feasible and safe for patients with distal BAO. |
| first_indexed | 2024-04-11T22:07:02Z |
| format | Article |
| id | doaj.art-3df3819710ca41a8a05460d21fd8e393 |
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| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-11T22:07:02Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-3df3819710ca41a8a05460d21fd8e3932022-12-22T04:00:40ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-08-011310.3389/fneur.2022.931507931507Endovascular treatment for distal basilar artery occlusion strokeJiaxing Song0Zhou Yu1Jian Wang2Xiaojun Luo3Jie Du4Zhengxuan Tian5Shunyu Yang6Weihua Xie7Yuqi Peng8Jinlin Mu9Wenjie Zi10Shuchun Huang11Mei Yang12Department of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, ChinaDepartment of Neurology, The First People's Hospital of Liangshan Yi Autonomous Prefecture, Sichuan, ChinaDepartment of Neurology, Ya'an People's Hospital, Sichuan, ChinaDepartment of Cerebrovascular Diseases, Guangyuan Central Hospital, Sichuan, ChinaDepartment of Neurology, Kaizhou District People's Hospital, Sichuan, ChinaDepartment of Neurology, The 404th Hospital of Mianyang, Sichuan, ChinaDepartment of Neurology, The First People's Hospital of Yunnan, Yunnan, ChinaDepartment of Neurology, People's Hospital of Mengzi, Yunnan, ChinaDepartment of Neurology, Sichuan Science City Hospital, Sichuan, China0Department of Neurology, Nanjiang County Traditional Chinese Medicine Hospital, Sichuan, ChinaDepartment of Neurology, Xinqiao Hospital and The Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China1Department of Neurology, Hospital 302 Attached to Guizhou Aviation Group, Guizhou, China2Department of Neurology, Dali Bai Autonomous Prefecture People's Hospital, Yunnan, ChinaBackgroundThis study aimed to investigate the clinical outcomes of endovascular treatment (EVT) for distal basilar artery occlusion (BAO) and compare them with the outcomes of standard medical treatment (SMT) in daily clinical practice.MethodsPatients with distal BAO enrolled in the BASILAR study from January 2014 to May 2019 were included. Differences in clinical outcomes were analyzed using Pearson's chi-square test and multivariable logistic regression. Clinical outcomes were evaluated using the modified Rankin Scale (mRS) score at 90 days, the mortality at 90 days, and the occurrence of symptomatic intracranial hemorrhage within 48 h.ResultsAmong the 267 patients with distal BAO (222 patients in the EVT group and 45 patients in the SMT group), compared with the SMT group, the EVT group was associated with a favorable outcome (mRS 0–3; 40.1 vs. 15.6%; aOR 5.44; 95% CI, 1.68–17.66; P = 0.005) and decreased mortality (44.6 vs. 71.1%, aOR 0.32, 95% CI, 0.13–0.77; P = 0.012). In the EVT group, multivariable analysis showed that the initial National Institutes of Health Stroke Scale (NIHSS) score and posterior circulation-Alberta Stroke Program Early CT Score (pc-ASPECTS) were associated with favorable functional outcomes and mortality.ConclusionOur study suggests that, compared with SMT, EVT is technically feasible and safe for patients with distal BAO.https://www.frontiersin.org/articles/10.3389/fneur.2022.931507/fullstrokedistal basilar artery occlusionendovascular treatment (EVT)occlusion siteacute basilar artery occlusion |
| spellingShingle | Jiaxing Song Zhou Yu Jian Wang Xiaojun Luo Jie Du Zhengxuan Tian Shunyu Yang Weihua Xie Yuqi Peng Jinlin Mu Wenjie Zi Shuchun Huang Mei Yang Endovascular treatment for distal basilar artery occlusion stroke Frontiers in Neurology stroke distal basilar artery occlusion endovascular treatment (EVT) occlusion site acute basilar artery occlusion |
| title | Endovascular treatment for distal basilar artery occlusion stroke |
| title_full | Endovascular treatment for distal basilar artery occlusion stroke |
| title_fullStr | Endovascular treatment for distal basilar artery occlusion stroke |
| title_full_unstemmed | Endovascular treatment for distal basilar artery occlusion stroke |
| title_short | Endovascular treatment for distal basilar artery occlusion stroke |
| title_sort | endovascular treatment for distal basilar artery occlusion stroke |
| topic | stroke distal basilar artery occlusion endovascular treatment (EVT) occlusion site acute basilar artery occlusion |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.931507/full |
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