RUNX2 Phosphorylation by Tyrosine Kinase ABL Promotes Breast Cancer Invasion

RUNX2 Phosphorylation by Tyrosine Kinase ABL Promotes Breast Cancer Invasion

Activity of transcription factors is normally regulated through interaction with other transcription factors, chromatin remodeling proteins and transcriptional co-activators. In distinction to these well-established transcriptional controls of gene expression, we have uncovered a unique activation m...

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Bibliographic Details
Main Authors: Fang He, Yoshinori Matsumoto, Yosuke Asano, Yuriko Yamamura, Takayuki Katsuyama, Jose La Rose, Nahoko Tomonobu, Ni Luh Gede Yoni Komalasari, Masakiyo Sakaguchi, Robert Rottapel, Jun Wada
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
ABL - Abelson murine leukemia viral oncogene homolog
Runx2 (runt-related transcription factor 2)
tyrosine
phosphorylation
invasion
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.665273/full

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