The serum proteome of VA-ECMO patients changes over time and allows differentiation of survivors and non-survivors: an observational study

The serum proteome of VA-ECMO patients changes over time and allows differentiation of survivors and non-survivors: an observational study

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is applied in patients with refractory hemodynamic failure. Exposure of blood components to high shear stress and the large extracorporeal surfaces in the ECMO circuit trigger a complex inflammatory response syndrome and...

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Bibliographic Details
Main Authors: Patrick Malcolm Siegel, Bálint András Barta, Lukas Orlean, Ines Derya Steenbuck, Miguel Cosenza-Contreras, Tobias Wengenmayer, Georg Trummer, Dennis Wolf, Dirk Westermann, Oliver Schilling, Philipp Diehl
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Translational Medicine
Subjects:
ECMO
Proteomics
Mortality
Inflammation
Coagulation
Complement
Online Access:https://doi.org/10.1186/s12967-023-04174-8

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