A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy
Super-resolution microscopy is a powerful tool for cellular studies but requires bright and stable fluorescent probes. Here, the authors report on a strategy to introduce quinoxaline motifs to conventional probes to make them brighter, more photostable, larger Stokes shift, and demonstrate the probe...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-29547-3 |
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author | Gangwei Jiang Tian-Bing Ren Elisa D’Este Mengyi Xiong Bin Xiong Kai Johnsson Xiao-Bing Zhang Lu Wang Lin Yuan |
author_facet | Gangwei Jiang Tian-Bing Ren Elisa D’Este Mengyi Xiong Bin Xiong Kai Johnsson Xiao-Bing Zhang Lu Wang Lin Yuan |
author_sort | Gangwei Jiang |
collection | DOAJ |
description | Super-resolution microscopy is a powerful tool for cellular studies but requires bright and stable fluorescent probes. Here, the authors report on a strategy to introduce quinoxaline motifs to conventional probes to make them brighter, more photostable, larger Stokes shift, and demonstrate the probes for biosensing applications. |
first_indexed | 2024-04-13T18:16:54Z |
format | Article |
id | doaj.art-3df8a774d0cd4bbb99426b8127963753 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-13T18:16:54Z |
publishDate | 2022-04-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-3df8a774d0cd4bbb99426b81279637532022-12-22T02:35:39ZengNature PortfolioNature Communications2041-17232022-04-0113111010.1038/s41467-022-29547-3A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopyGangwei Jiang0Tian-Bing Ren1Elisa D’Este2Mengyi Xiong3Bin Xiong4Kai Johnsson5Xiao-Bing Zhang6Lu Wang7Lin Yuan8State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan UniversityState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan UniversityOptical Microscopy Facility, Max Planck Institute for Medical ResearchState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan UniversityState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan UniversityDepartment of Chemical Biology, Max Planck Institute for Medical ResearchState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan UniversityDepartment of Chemical Biology, Max Planck Institute for Medical ResearchState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan UniversitySuper-resolution microscopy is a powerful tool for cellular studies but requires bright and stable fluorescent probes. Here, the authors report on a strategy to introduce quinoxaline motifs to conventional probes to make them brighter, more photostable, larger Stokes shift, and demonstrate the probes for biosensing applications.https://doi.org/10.1038/s41467-022-29547-3 |
spellingShingle | Gangwei Jiang Tian-Bing Ren Elisa D’Este Mengyi Xiong Bin Xiong Kai Johnsson Xiao-Bing Zhang Lu Wang Lin Yuan A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy Nature Communications |
title | A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy |
title_full | A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy |
title_fullStr | A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy |
title_full_unstemmed | A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy |
title_short | A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy |
title_sort | synergistic strategy to develop photostable and bright dyes with long stokes shift for nanoscopy |
url | https://doi.org/10.1038/s41467-022-29547-3 |
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