Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response
Legionella pneumophila expresses a range of bacterial determinants that mimic eukaryotic functions. Here the authors show small RNAs of L.pneumophila mimic eukaryotic microRNA and modulate the host response to infection.
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-28454-x |
| _version_ | 1819274905484525568 |
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| author | Tobias Sahr Pedro Escoll Christophe Rusniok Sheryl Bui Gérard Pehau-Arnaudet Gregory Lavieu Carmen Buchrieser |
| author_facet | Tobias Sahr Pedro Escoll Christophe Rusniok Sheryl Bui Gérard Pehau-Arnaudet Gregory Lavieu Carmen Buchrieser |
| author_sort | Tobias Sahr |
| collection | DOAJ |
| description | Legionella pneumophila expresses a range of bacterial determinants that mimic eukaryotic functions. Here the authors show small RNAs of L.pneumophila mimic eukaryotic microRNA and modulate the host response to infection. |
| first_indexed | 2024-12-23T23:15:51Z |
| format | Article |
| id | doaj.art-3df97bae629b4c4cb76dc65b011ff7e6 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-23T23:15:51Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-3df97bae629b4c4cb76dc65b011ff7e62022-12-21T17:26:31ZengNature PortfolioNature Communications2041-17232022-02-0113111810.1038/s41467-022-28454-xTranslocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune responseTobias Sahr0Pedro Escoll1Christophe Rusniok2Sheryl Bui3Gérard Pehau-Arnaudet4Gregory Lavieu5Carmen Buchrieser6Institut Pasteur, Université de Paris, Biologie des Bactéries Intracellulaires and CNRS UMR 6047Institut Pasteur, Université de Paris, Biologie des Bactéries Intracellulaires and CNRS UMR 6047Institut Pasteur, Université de Paris, Biologie des Bactéries Intracellulaires and CNRS UMR 6047Université de Paris, INSERM ERL U1316, UMR 7057/CNRSUnité de Technologie et Service BioImagerie Ultrastructurale and CNRS UMR 3528Université de Paris, INSERM ERL U1316, UMR 7057/CNRSInstitut Pasteur, Université de Paris, Biologie des Bactéries Intracellulaires and CNRS UMR 6047Legionella pneumophila expresses a range of bacterial determinants that mimic eukaryotic functions. Here the authors show small RNAs of L.pneumophila mimic eukaryotic microRNA and modulate the host response to infection.https://doi.org/10.1038/s41467-022-28454-x |
| spellingShingle | Tobias Sahr Pedro Escoll Christophe Rusniok Sheryl Bui Gérard Pehau-Arnaudet Gregory Lavieu Carmen Buchrieser Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response Nature Communications |
| title | Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response |
| title_full | Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response |
| title_fullStr | Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response |
| title_full_unstemmed | Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response |
| title_short | Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response |
| title_sort | translocated legionella pneumophila small rnas mimic eukaryotic micrornas targeting the host immune response |
| url | https://doi.org/10.1038/s41467-022-28454-x |
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