Developmental Coordination Disorder: State of the Art and Future Directions from a Neurophysiological Perspective
Developmental coordination disorder (DCD) is a common neurodevelopmental condition characterized by disabling motor impairments being visible from the first years of life. Over recent decades, research in this field has gained important results, showing alterations in several processes involved in t...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-06-01
|
| Series: | Children |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9067/9/7/945 |
| _version_ | 1827597576684175360 |
|---|---|
| author | Marco Emanuele Giovanni Polletta Maddalena Marini Luciano Fadiga |
| author_facet | Marco Emanuele Giovanni Polletta Maddalena Marini Luciano Fadiga |
| author_sort | Marco Emanuele |
| collection | DOAJ |
| description | Developmental coordination disorder (DCD) is a common neurodevelopmental condition characterized by disabling motor impairments being visible from the first years of life. Over recent decades, research in this field has gained important results, showing alterations in several processes involved in the regulation of motor behavior (e.g., planning and monitoring of actions, motor learning, action imitation). However, these studies mostly pursued a behavioral approach, leaving relevant questions open concerning the neural correlates of this condition. In this narrative review, we first survey the literature on motor control and sensorimotor impairments in DCD. Then, we illustrate the contributions to the field that may be achieved using transcranial magnetic stimulation (TMS) of the motor cortex. While still rarely employed in DCD research, this approach offers several opportunities, ranging from the clarification of low-level cortical electrophysiology to the assessment of the motor commands transmitted throughout the corticospinal system. We propose that TMS may help to investigate the neural correlates of motor impairments reported in behavioral studies, thus guiding DCD research toward a brain-oriented acknowledgment of this condition. This effort would help translational research to provide novel diagnostic and therapeutic tools. |
| first_indexed | 2024-03-09T03:34:25Z |
| format | Article |
| id | doaj.art-3e0126a2988146ec982c21b88c9ca953 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T03:34:25Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-3e0126a2988146ec982c21b88c9ca9532023-12-03T14:50:46ZengMDPI AGChildren2227-90672022-06-019794510.3390/children9070945Developmental Coordination Disorder: State of the Art and Future Directions from a Neurophysiological PerspectiveMarco Emanuele0Giovanni Polletta1Maddalena Marini2Luciano Fadiga3Section of Physiology, Department of Neuroscience and Rehabilitation, University of Ferrara, via Luigi Borsari 46, 44121 Ferrara, ItalySection of Physiology, Department of Neuroscience and Rehabilitation, University of Ferrara, via Luigi Borsari 46, 44121 Ferrara, ItalyIIT@UniFe Center for Translational Neurophysiology of Speech and Communication (CTNSC), Istituto Italiano di Tecnologia, via Fossato di Mortara 19, 44121 Ferrara, ItalySection of Physiology, Department of Neuroscience and Rehabilitation, University of Ferrara, via Luigi Borsari 46, 44121 Ferrara, ItalyDevelopmental coordination disorder (DCD) is a common neurodevelopmental condition characterized by disabling motor impairments being visible from the first years of life. Over recent decades, research in this field has gained important results, showing alterations in several processes involved in the regulation of motor behavior (e.g., planning and monitoring of actions, motor learning, action imitation). However, these studies mostly pursued a behavioral approach, leaving relevant questions open concerning the neural correlates of this condition. In this narrative review, we first survey the literature on motor control and sensorimotor impairments in DCD. Then, we illustrate the contributions to the field that may be achieved using transcranial magnetic stimulation (TMS) of the motor cortex. While still rarely employed in DCD research, this approach offers several opportunities, ranging from the clarification of low-level cortical electrophysiology to the assessment of the motor commands transmitted throughout the corticospinal system. We propose that TMS may help to investigate the neural correlates of motor impairments reported in behavioral studies, thus guiding DCD research toward a brain-oriented acknowledgment of this condition. This effort would help translational research to provide novel diagnostic and therapeutic tools.https://www.mdpi.com/2227-9067/9/7/945developmental coordination disorder (DCD)neurodevelopmental disorderstranscranial magnetic stimulation (TMS)motor developmentmotor control |
| spellingShingle | Marco Emanuele Giovanni Polletta Maddalena Marini Luciano Fadiga Developmental Coordination Disorder: State of the Art and Future Directions from a Neurophysiological Perspective Children developmental coordination disorder (DCD) neurodevelopmental disorders transcranial magnetic stimulation (TMS) motor development motor control |
| title | Developmental Coordination Disorder: State of the Art and Future Directions from a Neurophysiological Perspective |
| title_full | Developmental Coordination Disorder: State of the Art and Future Directions from a Neurophysiological Perspective |
| title_fullStr | Developmental Coordination Disorder: State of the Art and Future Directions from a Neurophysiological Perspective |
| title_full_unstemmed | Developmental Coordination Disorder: State of the Art and Future Directions from a Neurophysiological Perspective |
| title_short | Developmental Coordination Disorder: State of the Art and Future Directions from a Neurophysiological Perspective |
| title_sort | developmental coordination disorder state of the art and future directions from a neurophysiological perspective |
| topic | developmental coordination disorder (DCD) neurodevelopmental disorders transcranial magnetic stimulation (TMS) motor development motor control |
| url | https://www.mdpi.com/2227-9067/9/7/945 |
| work_keys_str_mv | AT marcoemanuele developmentalcoordinationdisorderstateoftheartandfuturedirectionsfromaneurophysiologicalperspective AT giovannipolletta developmentalcoordinationdisorderstateoftheartandfuturedirectionsfromaneurophysiologicalperspective AT maddalenamarini developmentalcoordinationdisorderstateoftheartandfuturedirectionsfromaneurophysiologicalperspective AT lucianofadiga developmentalcoordinationdisorderstateoftheartandfuturedirectionsfromaneurophysiologicalperspective |