Exploring metal availability in the natural niche of Streptococcus pneumoniae to discover potential vaccine antigens

Exploring metal availability in the natural niche of Streptococcus pneumoniae to discover potential vaccine antigens

Nasopharyngeal colonization by Streptococcus pneumoniae is a prerequisite for pneumococcal transmission and disease. Current vaccines protect only against disease and colonization caused by a limited number of serotypes, consequently allowing serotype replacement and transmission. Therefore, the dev...

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Bibliographic Details
Main Authors: Lucille F. van Beek, Kristin Surmann, H. Bart van den Berg van Saparoea, Diane Houben, Wouter S. P. Jong, Christian Hentschker, Thomas H. A. Ederveen, Elena Mitsi, Daniela M. Ferreira, Fred van Opzeeland, Christa E. van der Gaast – de Jongh, Irma Joosten, Uwe Völker, Frank Schmidt, Joen Luirink, Dimitri A. Diavatopoulos, Marien I. de Jonge
Format: Article
Language:English
Published: Taylor & Francis Group 2020-12-01
Series:Virulence
Subjects:
streptococcus pneumoniae
transition metals
nasal fluid
protein antigens
colonization
in vivo-mimicking
Online Access:http://dx.doi.org/10.1080/21505594.2020.1825908

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