Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy Systems
Objective: Bone marrow biopsy is an essential component in the diagnosis of hematopoietic disorders. Researchers evaluated the quality of bone marrow biopsy tissue acquired with a motorized bone marrow biopsy device versus a standard manual device based on the following criteria: biopsy length, perc...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-01-01
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| Series: | Asia-Pacific Journal of Oncology Nursing |
| Subjects: | |
| Online Access: | http://www.apjon.org/article.asp?issn=2347-5625;year=2018;volume=5;issue=4;spage=394;epage=398;aulast=Glennon |
| _version_ | 1797715903307055104 |
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| author | Catherine A Glennon Janet M Woodroof Suman Kambhampati Alexis C Battershell Serena R O'Connor Kiley B Roberts |
| author_facet | Catherine A Glennon Janet M Woodroof Suman Kambhampati Alexis C Battershell Serena R O'Connor Kiley B Roberts |
| author_sort | Catherine A Glennon |
| collection | DOAJ |
| description | Objective: Bone marrow biopsy is an essential component in the diagnosis of hematopoietic disorders. Researchers evaluated the quality of bone marrow biopsy tissue acquired with a motorized bone marrow biopsy device versus a standard manual device based on the following criteria: biopsy length, percentage of aspiration artifact/intrastromal hemorrhage, length of nonhematopoietic bone, and overall quality of the sample. Methods: Bone marrow biopsies (motorized, n = 30; manual, n = 120) from two academic medical centers were evaluated by two board-certified hematopathologists. For each specimen, the following parameters were recorded: biopsy length (cm), aspiration artifact (assessed in intervals of ≤10%, 11%–25%, 26%–50%, 51%–75%, and >75%), length (cm) of nonhematopoietic biopsy (e.g., cortical bone and skin), and overall quality of sample (inadequate, suboptimal, adequate, and excellent). Results: Operators from two centers included physicians and nurse practitioners. The manual system was superior to the powered drill with respect to the amount of crush artifact (0.15 cm ± 0.01 vs. 0.24 cm ± 0.04, P = 0.01 [t-test]). There was a trend toward less aspiration artifact/intrastromal hemorrhage with the use of the manual biopsy; however, the difference was not statistically significant (P = 0.06). There was no statistically significant difference in the overall biopsy size, biopsy length, amount of nonhematopoietic elements, and overall adequacy of the sample. Conclusions: There was no significant difference in the biopsy length, amount of nonhematopoietic elements, and overall adequacy of the sample. Results suggest that the manual bone marrow biopsy device has significantly less crush artifact of the specimen and has a trend toward less aspiration artifact/intrastromal hemorrhage as well. |
| first_indexed | 2024-03-12T08:13:42Z |
| format | Article |
| id | doaj.art-3e029a6ab2ca4526b90d88c89912eca9 |
| institution | Directory Open Access Journal |
| issn | 2347-5625 2349-6673 |
| language | English |
| last_indexed | 2024-03-12T08:13:42Z |
| publishDate | 2018-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asia-Pacific Journal of Oncology Nursing |
| spelling | doaj.art-3e029a6ab2ca4526b90d88c89912eca92023-09-02T19:00:22ZengElsevierAsia-Pacific Journal of Oncology Nursing2347-56252349-66732018-01-015439439810.4103/apjon.apjon_26_18Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy SystemsCatherine A GlennonJanet M WoodroofSuman KambhampatiAlexis C BattershellSerena R O'ConnorKiley B RobertsObjective: Bone marrow biopsy is an essential component in the diagnosis of hematopoietic disorders. Researchers evaluated the quality of bone marrow biopsy tissue acquired with a motorized bone marrow biopsy device versus a standard manual device based on the following criteria: biopsy length, percentage of aspiration artifact/intrastromal hemorrhage, length of nonhematopoietic bone, and overall quality of the sample. Methods: Bone marrow biopsies (motorized, n = 30; manual, n = 120) from two academic medical centers were evaluated by two board-certified hematopathologists. For each specimen, the following parameters were recorded: biopsy length (cm), aspiration artifact (assessed in intervals of ≤10%, 11%–25%, 26%–50%, 51%–75%, and >75%), length (cm) of nonhematopoietic biopsy (e.g., cortical bone and skin), and overall quality of sample (inadequate, suboptimal, adequate, and excellent). Results: Operators from two centers included physicians and nurse practitioners. The manual system was superior to the powered drill with respect to the amount of crush artifact (0.15 cm ± 0.01 vs. 0.24 cm ± 0.04, P = 0.01 [t-test]). There was a trend toward less aspiration artifact/intrastromal hemorrhage with the use of the manual biopsy; however, the difference was not statistically significant (P = 0.06). There was no statistically significant difference in the overall biopsy size, biopsy length, amount of nonhematopoietic elements, and overall adequacy of the sample. Conclusions: There was no significant difference in the biopsy length, amount of nonhematopoietic elements, and overall adequacy of the sample. Results suggest that the manual bone marrow biopsy device has significantly less crush artifact of the specimen and has a trend toward less aspiration artifact/intrastromal hemorrhage as well.http://www.apjon.org/article.asp?issn=2347-5625;year=2018;volume=5;issue=4;spage=394;epage=398;aulast=GlennonBone marrow aspiration and biopsycrush artifactmanual approachmotorized devicepathologyquality |
| spellingShingle | Catherine A Glennon Janet M Woodroof Suman Kambhampati Alexis C Battershell Serena R O'Connor Kiley B Roberts Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy Systems Asia-Pacific Journal of Oncology Nursing Bone marrow aspiration and biopsy crush artifact manual approach motorized device pathology quality |
| title | Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy Systems |
| title_full | Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy Systems |
| title_fullStr | Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy Systems |
| title_full_unstemmed | Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy Systems |
| title_short | Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy Systems |
| title_sort | comparison of bone marrow biopsy specimens obtained using a motorized device and manual biopsy systems |
| topic | Bone marrow aspiration and biopsy crush artifact manual approach motorized device pathology quality |
| url | http://www.apjon.org/article.asp?issn=2347-5625;year=2018;volume=5;issue=4;spage=394;epage=398;aulast=Glennon |
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