The Gene Polymorphism of the Angiotensin I-Converting Enzyme Correlates with Tumor Size and Patient Survival in Colorectal Cancer Patients

The Gene Polymorphism of the Angiotensin I-Converting Enzyme Correlates with Tumor Size and Patient Survival in Colorectal Cancer Patients

We studied the putative significance of angiotensin I-converting enzyme (ACE) in colorectal cancer (CRC) biology. Local expression of ACE was investigated by quantitative reverse transcription- polymerase chain reaction and by immunohistochemistry in CRCs and adenomas. ACE insertion (I)/deletion (D)...

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Bibliographic Details
Main Authors: Christoph Röcken, Konrad Neumann, Stacy Carl-McGrath, Hermann Lage, Matthias P.A. Ebert, Jutta Dierkes, Christoph A. Jacobi, Sinan Kalmuk, Peter Neuhaus, Ulf Neumann
Format: Article
Language:English
Published: Elsevier 2007-09-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Colorectal cancer
angiotensin-converting enzyme
polymorphism
gender
adenoma
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800315

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