Paronychia and granulation tissue formation during treatment with isotretinoin
Abstract This paper describes the association of two unusual side effects of treatment with isotretinoin for severe acne: paronychia and excess granulation tissue in the nails furrows. We report a case of male patient aged 19 years, who in the course of the 36th week of treatment with isotretinoin f...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2016-04-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200223&tlng=en |
| _version_ | 1798020588920373248 |
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| author | Daniela de Almeida Figueiras Ticiana Batista Ramos Ayana Karla de Oliveira Ferreira Marinho Milena Soneley Mendonça Bezerra Renata Cavalcanti Cauas |
| author_facet | Daniela de Almeida Figueiras Ticiana Batista Ramos Ayana Karla de Oliveira Ferreira Marinho Milena Soneley Mendonça Bezerra Renata Cavalcanti Cauas |
| author_sort | Daniela de Almeida Figueiras |
| collection | DOAJ |
| description | Abstract This paper describes the association of two unusual side effects of treatment with isotretinoin for severe acne: paronychia and excess granulation tissue in the nails furrows. We report a case of male patient aged 19 years, who in the course of the 36th week of treatment with isotretinoin for acne grade III showed erythema, edema, excess granulation tissue and onychocryptosis in various nail beds of hands and feet, with no history of trauma associated. A literature review revealed few reports of these adverse events, and two clinical patterns of exuberant granulation tissue has been described: one in periungual location and other in lesions of previous acne. The rarity and lack of knowledge on the best treatment for granuloma-like reactions make this theme a considerable challenge. |
| first_indexed | 2024-04-11T17:00:00Z |
| format | Article |
| id | doaj.art-3e06843308b8401788e4a0adc8ef35d4 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-04-11T17:00:00Z |
| publishDate | 2016-04-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-3e06843308b8401788e4a0adc8ef35d42022-12-22T04:13:10ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962016-04-0191222322510.1590/abd1806-4841.20163817Paronychia and granulation tissue formation during treatment with isotretinoinDaniela de Almeida FigueirasTiciana Batista RamosAyana Karla de Oliveira Ferreira MarinhoMilena Soneley Mendonça BezerraRenata Cavalcanti CauasAbstract This paper describes the association of two unusual side effects of treatment with isotretinoin for severe acne: paronychia and excess granulation tissue in the nails furrows. We report a case of male patient aged 19 years, who in the course of the 36th week of treatment with isotretinoin for acne grade III showed erythema, edema, excess granulation tissue and onychocryptosis in various nail beds of hands and feet, with no history of trauma associated. A literature review revealed few reports of these adverse events, and two clinical patterns of exuberant granulation tissue has been described: one in periungual location and other in lesions of previous acne. The rarity and lack of knowledge on the best treatment for granuloma-like reactions make this theme a considerable challenge.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200223&tlng=enParonychiaGranulation tissueRetinoids |
| spellingShingle | Daniela de Almeida Figueiras Ticiana Batista Ramos Ayana Karla de Oliveira Ferreira Marinho Milena Soneley Mendonça Bezerra Renata Cavalcanti Cauas Paronychia and granulation tissue formation during treatment with isotretinoin Anais Brasileiros de Dermatologia Paronychia Granulation tissue Retinoids |
| title | Paronychia and granulation tissue formation during treatment with isotretinoin |
| title_full | Paronychia and granulation tissue formation during treatment with isotretinoin |
| title_fullStr | Paronychia and granulation tissue formation during treatment with isotretinoin |
| title_full_unstemmed | Paronychia and granulation tissue formation during treatment with isotretinoin |
| title_short | Paronychia and granulation tissue formation during treatment with isotretinoin |
| title_sort | paronychia and granulation tissue formation during treatment with isotretinoin |
| topic | Paronychia Granulation tissue Retinoids |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000200223&tlng=en |
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