Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, the Polish Society of Allergology, the Polish Pediatric Society and the Polish Society of Family Medicine

Biological drugs in the treatment of atopic dermatitis – recommendations of the Polish Dermatological Society, the Polish Society of Allergology, the Polish Pediatric Society and the Polish Society of Family Medicine

The basis for development of atopic dermatitis are genetic, immunological and microbiological abnormalities as well as epidermal barrier defects. The course of the disease includes periodic exacerbations and remissions. Its development and course are influenced by numerous environmental and individ...

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Main Authors: Roman Nowicki, Magdalena Trzeciak, Lidia Rudnicka, Jacek Szepietowski, Marek Kulus, Maciej Kupczyk, Agnieszka Mastalerz-Migas, Jaroslaw Peregud-Pogorzelski, Karina Jahnz-Różyk, Joanna Narbutt, Magdalena Czarnecka-Operacz, Rafał Czajkowski, Elżbieta Grubska-Suchanek, Dorota Krasowska, Beata Kręcisz, Cezary Kowalewski, Aleksandra Lesiak, Małgorzata Olszewska, Zbigniew Samochocki, Radosław Śpiewak, Aleksandra Wilkowska
Format: Article
Language:English
Published: Termedia Publishing House 2020-12-01
Series:Przegląd Dermatologiczny
Subjects:
biological drugs
dupilumab
atopic dermatitis
therapeutic recommendations
Online Access:https://www.termedia.pl/Biological-drugs-in-the-treatment-of-atopic-dermatitis-recommendations-of-the-Polish-Dermatological-Society-the-Polish-Society-of-Allergology-the-Polish-Pediatric-Society-and-the-Polish-Society-of-Fam,56,42659,1,1.html
Description
Summary:The basis for development of atopic dermatitis are genetic, immunological and microbiological abnormalities as well as epidermal barrier defects. The course of the disease includes periodic exacerbations and remissions. Its development and course are influenced by numerous environmental and individual factors. In recent decades, in industrialized countries, a threefold increase in the incidence of atopic dermatitis was observed. There also is an increasing number of cases resistant to topical treatment. Effective treatment of atopic dermatitis should provide control of clinical symptoms, prevent exacerbations and improve the quality of life of patients. The multifactorial etiopathogenesis and various endotypes and phenotypes of the disease justify the tendency to optimize and personalize the therapy. Currently, we recommend the use of dupilumab for the treatment of patients from 12 years of age with moderate and severe atopic dermatitis, who do not respond to topical treatment.
ISSN:0033-2526
2084-9893

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