R-Spondin 2 and WNT/CTNNB1 Signaling Pathways Are Required for Porcine Follicle Development and In Vitro Maturation

R-Spondin 2 and WNT/CTNNB1 Signaling Pathways Are Required for Porcine Follicle Development and In Vitro Maturation

The secretion of oocyte-derived paracrine factors, such as R-spondin2, is an essential mechanism for follicle growth by promoting the proliferation and differentiation of cumulus cells around oocytes. In the present study, we aimed to identify the effect of R-spondin2 during follicular development....

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Bibliographic Details
Main Authors: Seon-Ung Hwang, Junchul David Yoon, Mirae Kim, Lian Cai, Hyerin Choi, Dongjin Oh, Eunhye Kim, Sang-Hwan Hyun
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Animals
Subjects:
porcine
in vitro maturation
cumulus cell
WNT/CTNNB1 pathway
RSPO2
Online Access:https://www.mdpi.com/2076-2615/11/3/709

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