Interleukin-1β and uric acid as potential second-trimester predictive biomarkers of preeclampsia
Methods: The prospective study was conducted at the University Hospital from February 2020 to December 2020. The study population (n = 88) included women who later developed PE (n = 42), as well as women who were healthy at birth (n = 46) in the second trimester of pregnancy. Serum levels of CRP, IL...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2021-07-01
|
| Series: | Hypertension in Pregnancy |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641955.2021.1921793 |
| _version_ | 1827814492183986176 |
|---|---|
| author | Keziban Dogan Alev Kural Yasin Oztoprak Murat Dogan |
| author_facet | Keziban Dogan Alev Kural Yasin Oztoprak Murat Dogan |
| author_sort | Keziban Dogan |
| collection | DOAJ |
| description | Methods: The prospective study was conducted at the University Hospital from February 2020 to December 2020. The study population (n = 88) included women who later developed PE (n = 42), as well as women who were healthy at birth (n = 46) in the second trimester of pregnancy. Serum levels of CRP, IL-1β, uric acid, creatinine, AST, ALT, MPV, Hb, PC, vitamin D, Ca, and Mg were compared between the groups. Results: Serum IL-1β and uric acid levels were significantly higher in subjects who eventually developed PE compared with those who did not. Conclusions: IL-1β and uric acid may be a predictive markers for PE. Maternal serum IL-1β and uric acid levels in the second trimester of pregnancy may be a predictive markers for PE. |
| first_indexed | 2024-03-11T23:45:47Z |
| format | Article |
| id | doaj.art-3e114e00fad4403782e9d9d268cf0fd3 |
| institution | Directory Open Access Journal |
| issn | 1064-1955 1525-6065 |
| language | English |
| last_indexed | 2024-03-11T23:45:47Z |
| publishDate | 2021-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hypertension in Pregnancy |
| spelling | doaj.art-3e114e00fad4403782e9d9d268cf0fd32023-09-19T09:24:44ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652021-07-0140318619210.1080/10641955.2021.19217931921793Interleukin-1β and uric acid as potential second-trimester predictive biomarkers of preeclampsiaKeziban Dogan0Alev Kural1Yasin Oztoprak2Murat Dogan3University of Health Sciences, Bakirköy Dr. Sadi Konuk Training and Research HospitalUniversity of Health Sciences, Bakirköy Dr. Sadi Konuk Training and Research HospitalUniversity of Health Sciences, Bakirköy Dr. Sadi Konuk Training and Research HospitalUniversity of Health Sciences, Bakirköy Dr. Sadi Konuk Training and Research HospitalMethods: The prospective study was conducted at the University Hospital from February 2020 to December 2020. The study population (n = 88) included women who later developed PE (n = 42), as well as women who were healthy at birth (n = 46) in the second trimester of pregnancy. Serum levels of CRP, IL-1β, uric acid, creatinine, AST, ALT, MPV, Hb, PC, vitamin D, Ca, and Mg were compared between the groups. Results: Serum IL-1β and uric acid levels were significantly higher in subjects who eventually developed PE compared with those who did not. Conclusions: IL-1β and uric acid may be a predictive markers for PE. Maternal serum IL-1β and uric acid levels in the second trimester of pregnancy may be a predictive markers for PE.http://dx.doi.org/10.1080/10641955.2021.1921793preeclampsiacrpinterleukin-1βuric acidmpvvitamin dcalciummagnesium |
| spellingShingle | Keziban Dogan Alev Kural Yasin Oztoprak Murat Dogan Interleukin-1β and uric acid as potential second-trimester predictive biomarkers of preeclampsia Hypertension in Pregnancy preeclampsia crp interleukin-1β uric acid mpv vitamin d calcium magnesium |
| title | Interleukin-1β and uric acid as potential second-trimester predictive biomarkers of preeclampsia |
| title_full | Interleukin-1β and uric acid as potential second-trimester predictive biomarkers of preeclampsia |
| title_fullStr | Interleukin-1β and uric acid as potential second-trimester predictive biomarkers of preeclampsia |
| title_full_unstemmed | Interleukin-1β and uric acid as potential second-trimester predictive biomarkers of preeclampsia |
| title_short | Interleukin-1β and uric acid as potential second-trimester predictive biomarkers of preeclampsia |
| title_sort | interleukin 1β and uric acid as potential second trimester predictive biomarkers of preeclampsia |
| topic | preeclampsia crp interleukin-1β uric acid mpv vitamin d calcium magnesium |
| url | http://dx.doi.org/10.1080/10641955.2021.1921793 |
| work_keys_str_mv | AT kezibandogan interleukin1banduricacidaspotentialsecondtrimesterpredictivebiomarkersofpreeclampsia AT alevkural interleukin1banduricacidaspotentialsecondtrimesterpredictivebiomarkersofpreeclampsia AT yasinoztoprak interleukin1banduricacidaspotentialsecondtrimesterpredictivebiomarkersofpreeclampsia AT muratdogan interleukin1banduricacidaspotentialsecondtrimesterpredictivebiomarkersofpreeclampsia |