Partitioning defective 6 homolog alpha (PARD6A) promotes epithelial–mesenchymal transition via integrin β1-ILK-SNAIL1 pathway in ovarian cancer
Abstract Partitioning-defective protein 6 (Par6) family proteins have been demonstrated to be closely associated with the occurrence and development of cancers. It is well accepted that dysregulation of epithelial–mesenchymal transition (EMT) greatly contributes to carcinogenesis and metastases of o...
Main Authors: | Ziwen Lu, Sirui Yuan, Lingling Ruan, Zhigang Tu, Hanqing Liu |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-04-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-04756-2 |
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