Oxidized low-density lipoprotein receptor 1: a novel potential therapeutic target for intracerebral hemorrhage

Oxidized low-density lipoprotein receptor 1: a novel potential therapeutic target for intracerebral hemorrhage

Oxidized low-density lipoprotein receptor 1 (OLR1) is upregulated in neurons and participates in hypertension-induced neuronal apoptosis. OLR1 deletion exerts protective effects on cerebral damage induced by hypertensive-induced stroke. Therefore, OLR1 is likely involved in the progress of intracere...

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Bibliographic Details
Main Authors: Hui-Yuan Zhang, Xi Lu, Yue-Han Hao, Ling Tang, Zhi-Yi He
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
ferroptosis; inflammation; intracerebral hemorrhage; neurological behavior; neuroprotection; novel therapeutic target; oxidative stress; oxidized low-density lipoprotein receptor 1; p38 signaling pathway; secondary brain injury
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=8;spage=1795;epage=1801;aulast=Zhang

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