Inflammatory Pseudotumor of the Sinonasal Tract

Inflammatory pseudotumors (IPTs) are a clinically and histologically diverse group of lesions characterized by a tumor mass of acute and chronic inflammatory cells with a variable fibrous response. IPTs most commonly involve the lung and orbit, but rarely the sinonasal tract. We report a 68-year-old...

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Main Authors: Chih-Chieh Chuang, Hou-Chun Lin, Chia-Wen Huang
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of the Formosan Medical Association
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664609602345
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author Chih-Chieh Chuang
Hou-Chun Lin
Chia-Wen Huang
author_facet Chih-Chieh Chuang
Hou-Chun Lin
Chia-Wen Huang
author_sort Chih-Chieh Chuang
collection DOAJ
description Inflammatory pseudotumors (IPTs) are a clinically and histologically diverse group of lesions characterized by a tumor mass of acute and chronic inflammatory cells with a variable fibrous response. IPTs most commonly involve the lung and orbit, but rarely the sinonasal tract. We report a 68-year-old male with an IPT of the sinonasal tract presenting as nasal obstruction and postnasal dripping for several years. A gray-white soft mass was noted in the right nasal cavity. Computed tomography revealed a solid mass filling the right nasal cavity and maxillary sinus. Caldwell-Luc operation with ethmoidectomy (right) was conducted to resect the mass en bloc. Pathology revealed admixture of plasma cells, lymphocytes and eosinophils, confirming the diagnosis of IPT. The patient remained symptom-free over 4 years of follow-up. Awareness of the clinical presentations, histopathologic features and treatment of choice of this rare disease entity is necessary to distinguish it from malignancy and avoid unnecessary management. [J Formos Med Assoc 2007;106(2):165-168]
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spelling doaj.art-3e15e7ecbb7b4f408d1ccee998dcb5342022-12-22T02:31:35ZengElsevierJournal of the Formosan Medical Association0929-66462007-01-01106216516810.1016/S0929-6646(09)60234-5Inflammatory Pseudotumor of the Sinonasal TractChih-Chieh Chuang0Hou-Chun Lin1Chia-Wen Huang2Department of Otolaryngology, Taipei City Hospital Yang-Ming Branch, Taipei, TaiwanDepartment of Otolaryngology, Taipei City Hospital Yang-Ming Branch, Taipei, TaiwanDepartment of Pathology, Taipei City Hospital Yang-Ming Branch, Taipei, TaiwanInflammatory pseudotumors (IPTs) are a clinically and histologically diverse group of lesions characterized by a tumor mass of acute and chronic inflammatory cells with a variable fibrous response. IPTs most commonly involve the lung and orbit, but rarely the sinonasal tract. We report a 68-year-old male with an IPT of the sinonasal tract presenting as nasal obstruction and postnasal dripping for several years. A gray-white soft mass was noted in the right nasal cavity. Computed tomography revealed a solid mass filling the right nasal cavity and maxillary sinus. Caldwell-Luc operation with ethmoidectomy (right) was conducted to resect the mass en bloc. Pathology revealed admixture of plasma cells, lymphocytes and eosinophils, confirming the diagnosis of IPT. The patient remained symptom-free over 4 years of follow-up. Awareness of the clinical presentations, histopathologic features and treatment of choice of this rare disease entity is necessary to distinguish it from malignancy and avoid unnecessary management. [J Formos Med Assoc 2007;106(2):165-168]http://www.sciencedirect.com/science/article/pii/S0929664609602345inflammatory pseudotumormaxillary sinusnasal cavityplasma cell granulomasinonasal tract
spellingShingle Chih-Chieh Chuang
Hou-Chun Lin
Chia-Wen Huang
Inflammatory Pseudotumor of the Sinonasal Tract
Journal of the Formosan Medical Association
inflammatory pseudotumor
maxillary sinus
nasal cavity
plasma cell granuloma
sinonasal tract
title Inflammatory Pseudotumor of the Sinonasal Tract
title_full Inflammatory Pseudotumor of the Sinonasal Tract
title_fullStr Inflammatory Pseudotumor of the Sinonasal Tract
title_full_unstemmed Inflammatory Pseudotumor of the Sinonasal Tract
title_short Inflammatory Pseudotumor of the Sinonasal Tract
title_sort inflammatory pseudotumor of the sinonasal tract
topic inflammatory pseudotumor
maxillary sinus
nasal cavity
plasma cell granuloma
sinonasal tract
url http://www.sciencedirect.com/science/article/pii/S0929664609602345
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