Automatic localization of the prostatic urethra for image guided radiation therapy

Treatment of prostate cancer with radiation therapy (RT) requires image guided RT (IGRT) to focus the radiation on the target volumes while minimizing doses to organs at risk. Here we describe a urinary catheter that allows imaging of the prostatic urethra and uses it for automatic localization of t...

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Main Authors: Nicola J. Nasser, Jonathan Klein, Eyal Fenig, Abed Agbarya
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Technical Innovations & Patient Support in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405632421000226
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author Nicola J. Nasser
Jonathan Klein
Eyal Fenig
Abed Agbarya
author_facet Nicola J. Nasser
Jonathan Klein
Eyal Fenig
Abed Agbarya
author_sort Nicola J. Nasser
collection DOAJ
description Treatment of prostate cancer with radiation therapy (RT) requires image guided RT (IGRT) to focus the radiation on the target volumes while minimizing doses to organs at risk. Here we describe a urinary catheter that allows imaging of the prostatic urethra and uses it for automatic localization of the prostate for IGRT. The catheter has a contrast lumen that can be empty or full with contrast. Computerized tomography is performed twice, with contrast lumen empty and full, allowing urethral autosegmentation using digital subtraction. Under ultrasound, continuous urethral visualization is possible by pumping aerated gel in- and out of the contrast lumen.
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spelling doaj.art-3e16aff23f7946abb49f6e30087e38da2022-12-21T17:16:08ZengElsevierTechnical Innovations & Patient Support in Radiation Oncology2405-63242021-09-011916Automatic localization of the prostatic urethra for image guided radiation therapyNicola J. Nasser0Jonathan Klein1Eyal Fenig2Abed Agbarya3Department of Radiation Oncology, University of Maryland School of Medicine, Maryland Proton Treatment Center, Baltimore, MD, USA; Corresponding author at: University of Maryland School of Medicine, Department of Radiation Oncology, Maryland Proton Treatment Center, Baltimore, MD, USA.Department of Radiation Oncology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, USAInstitute of Oncology, Davidoff Center, Rabin Medical Center, Beilinson Hospital, Petah Tikva, IsraelInstitute of Oncology, Bnai Zion Medical Center, Haifa, IsraelTreatment of prostate cancer with radiation therapy (RT) requires image guided RT (IGRT) to focus the radiation on the target volumes while minimizing doses to organs at risk. Here we describe a urinary catheter that allows imaging of the prostatic urethra and uses it for automatic localization of the prostate for IGRT. The catheter has a contrast lumen that can be empty or full with contrast. Computerized tomography is performed twice, with contrast lumen empty and full, allowing urethral autosegmentation using digital subtraction. Under ultrasound, continuous urethral visualization is possible by pumping aerated gel in- and out of the contrast lumen.http://www.sciencedirect.com/science/article/pii/S2405632421000226
spellingShingle Nicola J. Nasser
Jonathan Klein
Eyal Fenig
Abed Agbarya
Automatic localization of the prostatic urethra for image guided radiation therapy
Technical Innovations & Patient Support in Radiation Oncology
title Automatic localization of the prostatic urethra for image guided radiation therapy
title_full Automatic localization of the prostatic urethra for image guided radiation therapy
title_fullStr Automatic localization of the prostatic urethra for image guided radiation therapy
title_full_unstemmed Automatic localization of the prostatic urethra for image guided radiation therapy
title_short Automatic localization of the prostatic urethra for image guided radiation therapy
title_sort automatic localization of the prostatic urethra for image guided radiation therapy
url http://www.sciencedirect.com/science/article/pii/S2405632421000226
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