Adapted time-varying covariates Cox model for predicting future cirrhosis development performs well in a large hepatitis C cohort

Adapted time-varying covariates Cox model for predicting future cirrhosis development performs well in a large hepatitis C cohort

Abstract Background Patients with hepatitis C virus (HCV) frequently remain at risk for cirrhosis after sustained virologic response (SVR). Existing cirrhosis predictive models for HCV do not account for dynamic antiviral treatment status and are limited by fixed laboratory covariates and short foll...

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Bibliographic Details
Main Authors: Lauren A. Beste, Xuefei Zhang, Grace L. Su, Tony Van, George N. Ioannou, Brandon Oselio, Monica Tincopa, Boang Liu, Amit G. Singal, Ji Zhu, Akbar K. Waljee
Format: Article
Language:English
Published: BMC 2021-12-01
Series:BMC Medical Informatics and Decision Making
Subjects:
Veterans
Sustained virologic response
Hepatitis C virus
Survival model
Prediction
Online Access:https://doi.org/10.1186/s12911-021-01711-7

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