Development of a Luliconazole Nanoemulsion as a Prospective Ophthalmic Delivery System for the Treatment of Fungal Keratitis: In Vitro and In Vivo Evaluation

Development of a Luliconazole Nanoemulsion as a Prospective Ophthalmic Delivery System for the Treatment of Fungal Keratitis: In Vitro and In Vivo Evaluation

Luliconazole (LCZ), a novel imidazole drug, has broad-spectrum and potential antifungal effects, which makes it a possible cure for fungal keratitis; nevertheless, its medical use in ocular infections is hindered by its poor solubility. The purpose of this study was to design and optimize LCZ nanoem...

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Bibliographic Details
Main Authors: Jingjing Yang, Zhen Liang, Ping Lu, Fei Song, Zhen Zhang, Tianyang Zhou, Jingguo Li, Junjie Zhang
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
luliconazole
nanoemulsion
ocular drug delivery
fungal keratitis
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4923/14/10/2052

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https://www.mdpi.com/1999-4923/14/10/2052

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