Protection against brain injury after ischemic stroke by intravenous human amnion epithelial cells in combination with tissue plasminogen activator

Protection against brain injury after ischemic stroke by intravenous human amnion epithelial cells in combination with tissue plasminogen activator

BackgroundThrombolytic agents such as tissue plasminogen activator (tPA) are the only drug class approved to treat ischemic stroke and are usually administered within 4.5 h. However, only ~20% of ischemic stroke patients are eligible to receive the therapy. We previously demonstrated that early intr...

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Bibliographic Details
Main Authors: Liz J. Barreto-Arce, Hyun Ah Kim, Siow Teng Chan, Rebecca Lim, Grant R. Drummond, Henry Ma, Thanh G. Phan, Christopher G. Sobey, Shenpeng R. Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Neuroscience
Subjects:
ischemic stroke
neuroprotection
thrombolytic
stem cells
mouse
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1157236/full

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