ER stress response plays an important role in aggregation of α-synuclein

ER stress response plays an important role in aggregation of α-synuclein

<p>Abstract</p> <p>Background</p> <p>Accumulation of filamentous α-synuclein as Lewy bodies is a hallmark of Parkinson's disease. To identify the mechanisms involved in α-synuclein assembly and determine whether the assemblies are cytotoxic, we developed a cell mod...

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Bibliographic Details
Main Authors: Melrose Heather L, Lin Wen-Lang, Ebrahim Abdul, Gan Ming, Jiang Peizhou, Yen Shu-Hui C
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/56

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