Overlapping Genetic Architecture Between Schizophrenia and Neurodegenerative Disorders

Overlapping Genetic Architecture Between Schizophrenia and Neurodegenerative Disorders

Epidemiological and clinical studies have suggested comorbidity between schizophrenia and several neurodegenerative disorders. However, little is known whether there exists shared genetic architecture. To explore their relationship from a genetic and transcriptomic perspective, we applied polygenic...

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Bibliographic Details
Main Authors: Chunyu Li, Tianmi Yang, Ruwei Ou, Huifang Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TWAS
genetic correlation
schizophrenia
neurodegeneration
expression profiles
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.797072/full

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