Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors

Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors

Abstract Background Inflammation, metabolism, and epigenetic modulation are highly interconnected processes that can be altered during tumorigenesis. However, because of the complexity of these interactions, direct cause and effect during tumorigenesis have been difficult to prove. Previously, using...

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Bibliographic Details
Main Authors: Ashley R. Maiuri, Hongde Li, Barry D. Stein, Jason M. Tennessen, Heather M. O’Hagan
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cancer & Metabolism
Subjects:
Inflammation
DNA methylation
DNA polymerase gamma
Mitochondria
Glucose uptake
Glycolysis
Online Access:http://link.springer.com/article/10.1186/s40170-018-0182-7

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