Quartz Crystal Microbalance With Dissipation Monitoring: A Versatile Tool to Monitor Phase Transitions in Biomimetic Membranes
Solid-supported lipid membranes are popular models that connect biological and artificial materials used in bio-technological applications. Controlling the lipid organization and the related functions of these model systems entails understanding and characterizing their phase behavior. Quartz crysta...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-08-01
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| Series: | Frontiers in Materials |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fmats.2018.00046/full |
| _version_ | 1818876060722266112 |
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| author | Shova Neupane Shova Neupane Yana De Smet Frank U. Renner Frank U. Renner Patricia Losada-Pérez |
| author_facet | Shova Neupane Shova Neupane Yana De Smet Frank U. Renner Frank U. Renner Patricia Losada-Pérez |
| author_sort | Shova Neupane |
| collection | DOAJ |
| description | Solid-supported lipid membranes are popular models that connect biological and artificial materials used in bio-technological applications. Controlling the lipid organization and the related functions of these model systems entails understanding and characterizing their phase behavior. Quartz crystal microbalance with dissipation monitoring (QCM-D) is an acoustic-based surface-sensitive technique which is widely used in bio-interfacial science of solid-supported lipid membranes. Its sensitivity to mass and energy dissipation changes at the solid-lipid layer-liquid interface allows the detection of phase transformations of solid-supported membrane geometries. In this perspective, we highlight this valuable feature and its related methodology, review current advances and briefly discuss future perspectives. Furthermore, a specific example is also provided on the ability of QCM-D to detect changes in lipid organization of cholesterol containing solid-supported lipid vesicle layers (SVLs) upon the addition of aspirin. |
| first_indexed | 2024-12-19T13:36:23Z |
| format | Article |
| id | doaj.art-3e307860ce0a4da6bdeff458cd49e16b |
| institution | Directory Open Access Journal |
| issn | 2296-8016 |
| language | English |
| last_indexed | 2024-12-19T13:36:23Z |
| publishDate | 2018-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Materials |
| spelling | doaj.art-3e307860ce0a4da6bdeff458cd49e16b2022-12-21T20:19:11ZengFrontiers Media S.A.Frontiers in Materials2296-80162018-08-01510.3389/fmats.2018.00046403619Quartz Crystal Microbalance With Dissipation Monitoring: A Versatile Tool to Monitor Phase Transitions in Biomimetic MembranesShova Neupane0Shova Neupane1Yana De Smet2Frank U. Renner3Frank U. Renner4Patricia Losada-Pérez5Institute for Materials Research, Hasselt University, Diepenbeek, BelgiumIMEC vzw Division IMOMEC, Diepenbeek, BelgiumInstitute for Materials Research, Hasselt University, Diepenbeek, BelgiumInstitute for Materials Research, Hasselt University, Diepenbeek, BelgiumIMEC vzw Division IMOMEC, Diepenbeek, BelgiumSoft Matter Physics Laboratory, Université Libre de Bruxelles, Campus La Plaine, Brussels, BelgiumSolid-supported lipid membranes are popular models that connect biological and artificial materials used in bio-technological applications. Controlling the lipid organization and the related functions of these model systems entails understanding and characterizing their phase behavior. Quartz crystal microbalance with dissipation monitoring (QCM-D) is an acoustic-based surface-sensitive technique which is widely used in bio-interfacial science of solid-supported lipid membranes. Its sensitivity to mass and energy dissipation changes at the solid-lipid layer-liquid interface allows the detection of phase transformations of solid-supported membrane geometries. In this perspective, we highlight this valuable feature and its related methodology, review current advances and briefly discuss future perspectives. Furthermore, a specific example is also provided on the ability of QCM-D to detect changes in lipid organization of cholesterol containing solid-supported lipid vesicle layers (SVLs) upon the addition of aspirin.https://www.frontiersin.org/article/10.3389/fmats.2018.00046/fullQCM-Dmodel mebranesphase transitions biological condensed matterviscoelastic propertiesbiointerfaces |
| spellingShingle | Shova Neupane Shova Neupane Yana De Smet Frank U. Renner Frank U. Renner Patricia Losada-Pérez Quartz Crystal Microbalance With Dissipation Monitoring: A Versatile Tool to Monitor Phase Transitions in Biomimetic Membranes Frontiers in Materials QCM-D model mebranes phase transitions biological condensed matter viscoelastic properties biointerfaces |
| title | Quartz Crystal Microbalance With Dissipation Monitoring: A Versatile Tool to Monitor Phase Transitions in Biomimetic Membranes |
| title_full | Quartz Crystal Microbalance With Dissipation Monitoring: A Versatile Tool to Monitor Phase Transitions in Biomimetic Membranes |
| title_fullStr | Quartz Crystal Microbalance With Dissipation Monitoring: A Versatile Tool to Monitor Phase Transitions in Biomimetic Membranes |
| title_full_unstemmed | Quartz Crystal Microbalance With Dissipation Monitoring: A Versatile Tool to Monitor Phase Transitions in Biomimetic Membranes |
| title_short | Quartz Crystal Microbalance With Dissipation Monitoring: A Versatile Tool to Monitor Phase Transitions in Biomimetic Membranes |
| title_sort | quartz crystal microbalance with dissipation monitoring a versatile tool to monitor phase transitions in biomimetic membranes |
| topic | QCM-D model mebranes phase transitions biological condensed matter viscoelastic properties biointerfaces |
| url | https://www.frontiersin.org/article/10.3389/fmats.2018.00046/full |
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