DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning
Abstract Recent technological advances have enabled DNA methylation to be assayed at single-cell resolution. However, current protocols are limited by incomplete CpG coverage and hence methods to predict missing methylation states are critical to enable genome-wide analyses. We report DeepCpG, a com...
| Автори: | , , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
BMC
2017-04-01
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| Серія: | Genome Biology |
| Предмети: | |
| Онлайн доступ: | http://link.springer.com/article/10.1186/s13059-017-1189-z |