Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury

Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury

Deep brain stimulation and epidural electrical stimulation of the spinal cord enable locomotion in humans with spinal cord injury (SCI) but the potential synergy between both approaches is unclear. The authors show that a complex technological approach is required to enable volitional walking in rat...

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Bibliographic Details
Main Authors: Marco Bonizzato, Nicholas D. James, Galyna Pidpruzhnykova, Natalia Pavlova, Polina Shkorbatova, Laetitia Baud, Cristina Martinez-Gonzalez, Jordan W. Squair, Jack DiGiovanna, Quentin Barraud, Silvestro Micera, Gregoire Courtine
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22137-9

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