Prevalence of Conventional Risk Factors in Acute Coronary Syndrome Patients in Eastern Part of Nepal

Background: Smoking, diabetes mellitus, hypertension and dyslipidemia are known as conventional risk factors of coronary artery disease (CAD) and the prevalence of it varies across populations. There is paucity of data in our country about the prevalence of risk factors for acute coronary syndrome (...

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Main Authors: Rajesh Nepal, Madhav Bista, Abdul Khaliq Monib, Manoj Kumar Choudhary, Aakriti Bhattarai
Format: Article
Language:English
Published: Nobel Medical College Teaching Hospital 2017-08-01
Series:Journal of Nobel Medical College
Subjects:
Online Access:https://www.nepjol.info/index.php/JoNMC/article/view/18087
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author Rajesh Nepal
Madhav Bista
Abdul Khaliq Monib
Manoj Kumar Choudhary
Aakriti Bhattarai
author_facet Rajesh Nepal
Madhav Bista
Abdul Khaliq Monib
Manoj Kumar Choudhary
Aakriti Bhattarai
author_sort Rajesh Nepal
collection DOAJ
description Background: Smoking, diabetes mellitus, hypertension and dyslipidemia are known as conventional risk factors of coronary artery disease (CAD) and the prevalence of it varies across populations. There is paucity of data in our country about the prevalence of risk factors for acute coronary syndrome (ACS). This study aims to assess the prevalence of these conventional risk factors in patients who were admitted in Nobel medical college, with the diagnosis of ACS. Material & Methods: In this observational study, we enrolled 102 patients diagnosed as ACS with stenosis ≥50% of any epicardial arteries as shown on angiography admitted in Nobel Medical College between September 2015 to March 2017 and evaluate the prevalence of conventional risk factors. In addition, we analyzed the lipid profiles within 24 hour of the event. Results: Mean age of the patients was 59 years. Two third (66.7%) of the patients were male. Left anterior descending artery (43.13%) was the most common culprit lesion followed by RCA in 35.29%. Dyslipidemia was present in 73.5%, hypertension in 46.1%, smoking in 38.2% and diabetes in 37.3%. Prevalence of hypertension, diabetes and dyslipidemia was similar among male and female. Smoking (44.1%vs26.5%) was more common in male (P=<0.05). TG ≥150 mg/dl was seen in 52% study population and higher level of TG was seen in younger population ≤45 years compared to ≥45 years old (p=0.013). Conclusion: Present study showed high prevalence of hypertension, smoking, diabetes and dyslipidemia in patients with ACS, suggesting the need of aggressive risk factor reduction in general population.  Journal of Nobel Medical College Volume 6, Number 1, Issue 10 (January-June, 2017), page: 48-55
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spelling doaj.art-3e3467d120634af2b19e09f58013be222022-12-22T00:52:00ZengNobel Medical College Teaching HospitalJournal of Nobel Medical College2091-23312091-234X2017-08-0161485510.3126/jonmc.v6i1.1808718087Prevalence of Conventional Risk Factors in Acute Coronary Syndrome Patients in Eastern Part of NepalRajesh Nepal0Madhav Bista1Abdul Khaliq Monib2Manoj Kumar Choudhary3Aakriti Bhattarai4Department of Internal Medicine, Cardiology Unit, Nobel Medical College Teaching Hospital, BiratnagarDepartment of Internal Medicine, Cardiology Unit, Nobel Medical College Teaching Hospital, BiratnagarDepartment of Internal Medicine, Cardiology Unit, Nobel Medical College Teaching Hospital, BiratnagarDepartment of Internal Medicine, Cardiology Unit, Nobel Medical College Teaching Hospital, BiratnagarDepartment of Internal Medicine, Cardiology Unit, Nobel Medical College Teaching Hospital, BiratnagarBackground: Smoking, diabetes mellitus, hypertension and dyslipidemia are known as conventional risk factors of coronary artery disease (CAD) and the prevalence of it varies across populations. There is paucity of data in our country about the prevalence of risk factors for acute coronary syndrome (ACS). This study aims to assess the prevalence of these conventional risk factors in patients who were admitted in Nobel medical college, with the diagnosis of ACS. Material & Methods: In this observational study, we enrolled 102 patients diagnosed as ACS with stenosis ≥50% of any epicardial arteries as shown on angiography admitted in Nobel Medical College between September 2015 to March 2017 and evaluate the prevalence of conventional risk factors. In addition, we analyzed the lipid profiles within 24 hour of the event. Results: Mean age of the patients was 59 years. Two third (66.7%) of the patients were male. Left anterior descending artery (43.13%) was the most common culprit lesion followed by RCA in 35.29%. Dyslipidemia was present in 73.5%, hypertension in 46.1%, smoking in 38.2% and diabetes in 37.3%. Prevalence of hypertension, diabetes and dyslipidemia was similar among male and female. Smoking (44.1%vs26.5%) was more common in male (P=<0.05). TG ≥150 mg/dl was seen in 52% study population and higher level of TG was seen in younger population ≤45 years compared to ≥45 years old (p=0.013). Conclusion: Present study showed high prevalence of hypertension, smoking, diabetes and dyslipidemia in patients with ACS, suggesting the need of aggressive risk factor reduction in general population.  Journal of Nobel Medical College Volume 6, Number 1, Issue 10 (January-June, 2017), page: 48-55https://www.nepjol.info/index.php/JoNMC/article/view/18087acute coronary syndromediabetesdyslipidemiahypertensionsmoking
spellingShingle Rajesh Nepal
Madhav Bista
Abdul Khaliq Monib
Manoj Kumar Choudhary
Aakriti Bhattarai
Prevalence of Conventional Risk Factors in Acute Coronary Syndrome Patients in Eastern Part of Nepal
Journal of Nobel Medical College
acute coronary syndrome
diabetes
dyslipidemia
hypertension
smoking
title Prevalence of Conventional Risk Factors in Acute Coronary Syndrome Patients in Eastern Part of Nepal
title_full Prevalence of Conventional Risk Factors in Acute Coronary Syndrome Patients in Eastern Part of Nepal
title_fullStr Prevalence of Conventional Risk Factors in Acute Coronary Syndrome Patients in Eastern Part of Nepal
title_full_unstemmed Prevalence of Conventional Risk Factors in Acute Coronary Syndrome Patients in Eastern Part of Nepal
title_short Prevalence of Conventional Risk Factors in Acute Coronary Syndrome Patients in Eastern Part of Nepal
title_sort prevalence of conventional risk factors in acute coronary syndrome patients in eastern part of nepal
topic acute coronary syndrome
diabetes
dyslipidemia
hypertension
smoking
url https://www.nepjol.info/index.php/JoNMC/article/view/18087
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