Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)

Two flavonoid compounds, kaempferol (1) and quercetin (2) have been isolated from the leaves of Rasamala (Altingia excelsa Nornha). The chemical structure of compounds 1 and 2 were identified by spectroscopic evidences including, UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously...

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Bibliografische gegevens
Hoofdauteurs: Risyandi Anwar, Arlette Setiawan, Supriatno Supriatno, Unang Supratman
Formaat: Artikel
Taal:Indonesian
Gepubliceerd in: Syarif Hidayatullah Jakarta State Islamic University 2018-11-01
Reeks:Jurnal Kimia Valensi
Onderwerpen:
Online toegang:http://journal.uinjkt.ac.id/index.php/valensi/article/view/7304
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author Risyandi Anwar
Arlette Setiawan
Supriatno Supriatno
Unang Supratman
author_facet Risyandi Anwar
Arlette Setiawan
Supriatno Supriatno
Unang Supratman
author_sort Risyandi Anwar
collection DOAJ
description Two flavonoid compounds, kaempferol (1) and quercetin (2) have been isolated from the leaves of Rasamala (Altingia excelsa Nornha). The chemical structure of compounds 1 and 2 were identified by spectroscopic evidences including, UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data.These compounds were isolated from this plant for the first time. Compounds 1 and 2 were evaluated for their antiproliferative activity against SP-C1 cancer tongue cells and showed IC50 values of 2.50 and 2.31 mM, respectively.
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publisher Syarif Hidayatullah Jakarta State Islamic University
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spelling doaj.art-3e363ec0fdad4d99961e7b5ea572b51a2022-12-22T01:35:59ZindSyarif Hidayatullah Jakarta State Islamic UniversityJurnal Kimia Valensi2460-60652548-30132018-11-0142757810.15408/jkv.v4i2.73044919Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)Risyandi Anwar0Arlette Setiawan1Supriatno Supriatno2Unang Supratman3Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Muhammadiyah, Semarang 50273, Central Java, Indonesia.Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia.Departemen Kimia FakulDepartment of Oral Medicine, Faculty of Dentistry, Universitas Gadjah Mada, Jogjakarta 50125, Indonesia.Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia. Central Laboratory, Universitas Padjadjaran, Jatinangor 45363, West Java, IndonesiaTwo flavonoid compounds, kaempferol (1) and quercetin (2) have been isolated from the leaves of Rasamala (Altingia excelsa Nornha). The chemical structure of compounds 1 and 2 were identified by spectroscopic evidences including, UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data.These compounds were isolated from this plant for the first time. Compounds 1 and 2 were evaluated for their antiproliferative activity against SP-C1 cancer tongue cells and showed IC50 values of 2.50 and 2.31 mM, respectively.http://journal.uinjkt.ac.id/index.php/valensi/article/view/7304altingia excelsa, sp-c1 cancer tongue cells, kaempferol, quercetin
spellingShingle Risyandi Anwar
Arlette Setiawan
Supriatno Supriatno
Unang Supratman
Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)
Jurnal Kimia Valensi
altingia excelsa, sp-c1 cancer tongue cells, kaempferol, quercetin
title Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)
title_full Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)
title_fullStr Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)
title_full_unstemmed Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)
title_short Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)
title_sort two flavonoid compounds as antiproliferative activity against sp c1 cancer tongue cells from the leaves of rasamala altingia excelsa nornha
topic altingia excelsa, sp-c1 cancer tongue cells, kaempferol, quercetin
url http://journal.uinjkt.ac.id/index.php/valensi/article/view/7304
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