Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)
Two flavonoid compounds, kaempferol (1) and quercetin (2) have been isolated from the leaves of Rasamala (Altingia excelsa Nornha). The chemical structure of compounds 1 and 2 were identified by spectroscopic evidences including, UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously...
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Formaat: | Artikel |
Taal: | Indonesian |
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Syarif Hidayatullah Jakarta State Islamic University
2018-11-01
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Reeks: | Jurnal Kimia Valensi |
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Online toegang: | http://journal.uinjkt.ac.id/index.php/valensi/article/view/7304 |
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author | Risyandi Anwar Arlette Setiawan Supriatno Supriatno Unang Supratman |
author_facet | Risyandi Anwar Arlette Setiawan Supriatno Supriatno Unang Supratman |
author_sort | Risyandi Anwar |
collection | DOAJ |
description | Two flavonoid compounds, kaempferol (1) and quercetin (2) have been isolated from the leaves of Rasamala (Altingia excelsa Nornha). The chemical structure of compounds 1 and 2 were identified by spectroscopic evidences including, UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data.These compounds were isolated from this plant for the first time. Compounds 1 and 2 were evaluated for their antiproliferative activity against SP-C1 cancer tongue cells and showed IC50 values of 2.50 and 2.31 mM, respectively. |
first_indexed | 2024-12-10T19:41:27Z |
format | Article |
id | doaj.art-3e363ec0fdad4d99961e7b5ea572b51a |
institution | Directory Open Access Journal |
issn | 2460-6065 2548-3013 |
language | Indonesian |
last_indexed | 2024-12-10T19:41:27Z |
publishDate | 2018-11-01 |
publisher | Syarif Hidayatullah Jakarta State Islamic University |
record_format | Article |
series | Jurnal Kimia Valensi |
spelling | doaj.art-3e363ec0fdad4d99961e7b5ea572b51a2022-12-22T01:35:59ZindSyarif Hidayatullah Jakarta State Islamic UniversityJurnal Kimia Valensi2460-60652548-30132018-11-0142757810.15408/jkv.v4i2.73044919Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha)Risyandi Anwar0Arlette Setiawan1Supriatno Supriatno2Unang Supratman3Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Muhammadiyah, Semarang 50273, Central Java, Indonesia.Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia.Departemen Kimia FakulDepartment of Oral Medicine, Faculty of Dentistry, Universitas Gadjah Mada, Jogjakarta 50125, Indonesia.Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, West Java, Indonesia. Central Laboratory, Universitas Padjadjaran, Jatinangor 45363, West Java, IndonesiaTwo flavonoid compounds, kaempferol (1) and quercetin (2) have been isolated from the leaves of Rasamala (Altingia excelsa Nornha). The chemical structure of compounds 1 and 2 were identified by spectroscopic evidences including, UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data.These compounds were isolated from this plant for the first time. Compounds 1 and 2 were evaluated for their antiproliferative activity against SP-C1 cancer tongue cells and showed IC50 values of 2.50 and 2.31 mM, respectively.http://journal.uinjkt.ac.id/index.php/valensi/article/view/7304altingia excelsa, sp-c1 cancer tongue cells, kaempferol, quercetin |
spellingShingle | Risyandi Anwar Arlette Setiawan Supriatno Supriatno Unang Supratman Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha) Jurnal Kimia Valensi altingia excelsa, sp-c1 cancer tongue cells, kaempferol, quercetin |
title | Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha) |
title_full | Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha) |
title_fullStr | Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha) |
title_full_unstemmed | Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha) |
title_short | Two Flavonoid Compounds as Antiproliferative Activity Against SP-C1 Cancer Tongue Cells from the Leaves of Rasamala (Altingia excelsa Nornha) |
title_sort | two flavonoid compounds as antiproliferative activity against sp c1 cancer tongue cells from the leaves of rasamala altingia excelsa nornha |
topic | altingia excelsa, sp-c1 cancer tongue cells, kaempferol, quercetin |
url | http://journal.uinjkt.ac.id/index.php/valensi/article/view/7304 |
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