Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells

Inflammatory and deleterious role of gut microbiota-derived trimethylamine on colon cells

Trimethylamine (TMA) is produced by the intestinal microbiota as a by-product of metabolism of dietary precursors. TMA has been implicated in various chronic health conditions. However, the effect of TMA in the colon and the underlying mechanism was not clear. In this study, TMA exhibited toxic effe...

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Bibliographic Details
Main Authors: Rekha Jalandra, Govind K. Makharia, Minakshi Sharma, Anil Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
metabolite
TMA
genotoxic
cytotoxic
colorectal cancer
trimethylamine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1101429/full

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