The Groucho co-repressor is primarily recruited to local target sites in active chromatin to attenuate transcription.
Gene expression is regulated by the complex interaction between transcriptional activators and repressors, which function in part by recruiting histone-modifying enzymes to control accessibility of DNA to RNA polymerase. The evolutionarily conserved family of Groucho/Transducin-Like Enhancer of spli...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-08-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4148212?pdf=render |