Identification of Driver Genes Regulating the T-Cell–Infiltrating Levels in Hepatocellular Carcinoma

Identification of Driver Genes Regulating the T-Cell–Infiltrating Levels in Hepatocellular Carcinoma

The driver genes regulating T-cell infiltration are important for understanding immune-escape mechanisms and developing more effective immunotherapy. However, researches in this field have rarely been reported in hepatocellular carcinoma (HCC). In the present study, we identified cancer driver genes...

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Bibliographic Details
Main Authors: Yi Cai, Ying Tian, Jianchu Wang, Wang Wei, Qianli Tang, Libai Lu, Zongjiang Luo, Wenchuan Li, Yuan Lu, Jian Pu, Zhengxia Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Genetics
Subjects:
T-cell infiltration
cancer immunotherapy
immune escape
driver gene
oncogenic pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.560546/full

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