Relationship between Vitamin C and Length of Hospital Stay for Covid-19 Patients with Comorbidities

Covid-19 patients with comorbidities, such as hypertension, diabetes, and respiratory diseases, have a higher risk for severe disease and mortality compared to patients without comorbidities. Some data shows that the administration of high dose vitamin C (1–2 g/day) can reduce the amount of the infl...

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Main Authors: Budiyanti Wiboworini, Amelya Augusthina Ayusari, Risalina Myrtha, Dwi Rahayu, Widardo Widardo, Yulia Lanti, Amalina Shabrina, Joko Sudarsono, Sutartinah Sri Handayani, Graciella Angelica Lucas
Format: Article
Language:English
Published: Universitas Padjajaran 2022-03-01
Series:Majalah Kedokteran Bandung
Subjects:
Online Access:http://journal.fk.unpad.ac.id/index.php/mkb/article/view/2582
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author Budiyanti Wiboworini
Amelya Augusthina Ayusari
Risalina Myrtha
Dwi Rahayu
Widardo Widardo
Yulia Lanti
Amalina Shabrina
Joko Sudarsono
Sutartinah Sri Handayani
Graciella Angelica Lucas
author_facet Budiyanti Wiboworini
Amelya Augusthina Ayusari
Risalina Myrtha
Dwi Rahayu
Widardo Widardo
Yulia Lanti
Amalina Shabrina
Joko Sudarsono
Sutartinah Sri Handayani
Graciella Angelica Lucas
author_sort Budiyanti Wiboworini
collection DOAJ
description Covid-19 patients with comorbidities, such as hypertension, diabetes, and respiratory diseases, have a higher risk for severe disease and mortality compared to patients without comorbidities. Some data shows that the administration of high dose vitamin C (1–2 g/day) can reduce the amount of the inflammatory mediators and shorten the length of hospital stay. This study aimed to determine the relationship between vitamin C administration and of length of hospital stay for Covid-19 patients with comorbidities. This study was a retrospective observational study on  consecutively sampled medical record data of UNS Hospital patients from July 2020 to January 2021. A total of 78 patient medical records were included of this study. The inclusion criteria were all medical records of patients who suffered from Covid-19 with comorbidities admitted to the hospital while the exclusion criteria were medical records of patients who did not get oral or intravenous vitamin C. The chi-square bivariate test was used to determine the relationship between the administration of vitamin C and the length of hospital stay for Covid-19 patients with comorbidities. Of the 78 subjects only 52 subjects were included in the statistical analysis. Medical records were divided into two groups: group 1, that consisted of medical records of patient who received more than 1,000 mg Vitamin C, and group 2, who received less than 1,000 mg Vitamin C. Results demonstrated that the administration of high dose vitamin C of more than 1,000 mg was not associated with the length of hospital stay (p=0.677). Thus, high dose of vitamin C is not associated with the length of hospital stay for Covid-19 patients with comorbidities, such as hypertension, diabetes, and respiratory disease.
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spelling doaj.art-3e3c9a10d4fb4bf187b3fb52ef4ae2a72022-12-22T02:27:29ZengUniversitas PadjajaranMajalah Kedokteran Bandung0126-074X2338-62232022-03-01541141910.15395/mkb.v54n1.25821416Relationship between Vitamin C and Length of Hospital Stay for Covid-19 Patients with ComorbiditiesBudiyanti Wiboworini0Amelya Augusthina Ayusari1Risalina Myrtha2Dwi Rahayu3Widardo Widardo4Yulia Lanti5Amalina Shabrina6Joko Sudarsono7Sutartinah Sri Handayani8Graciella Angelica Lucas9Nutrition Department, Faculty of Medicine, Universitas Sebelas MaretNutrition Department, Faculty of Medicine, Universitas Sebelas Maret, SoloFaculty of Medicine, Universitas Sebelas Maret/Dr. Moewardi Hospital SurakartaNutrition Department, Faculty of Medicine, Universitas Sebelas MaretNutrition Department, Faculty of Medicine, Universitas Sebelas MaretNutrition Department, Faculty of Medicine, Universitas Sebelas MaretNutrition Department, Faculty of Medicine, Universitas Sebelas MaretUniversitas Sebelas Maret Hospital, SoloParasitology Laboratory, Faculty of Medicine, Universitas Sebelas Maret, SoloFaculty of Medicine, Universitas Sebelas Maret, SoloCovid-19 patients with comorbidities, such as hypertension, diabetes, and respiratory diseases, have a higher risk for severe disease and mortality compared to patients without comorbidities. Some data shows that the administration of high dose vitamin C (1–2 g/day) can reduce the amount of the inflammatory mediators and shorten the length of hospital stay. This study aimed to determine the relationship between vitamin C administration and of length of hospital stay for Covid-19 patients with comorbidities. This study was a retrospective observational study on  consecutively sampled medical record data of UNS Hospital patients from July 2020 to January 2021. A total of 78 patient medical records were included of this study. The inclusion criteria were all medical records of patients who suffered from Covid-19 with comorbidities admitted to the hospital while the exclusion criteria were medical records of patients who did not get oral or intravenous vitamin C. The chi-square bivariate test was used to determine the relationship between the administration of vitamin C and the length of hospital stay for Covid-19 patients with comorbidities. Of the 78 subjects only 52 subjects were included in the statistical analysis. Medical records were divided into two groups: group 1, that consisted of medical records of patient who received more than 1,000 mg Vitamin C, and group 2, who received less than 1,000 mg Vitamin C. Results demonstrated that the administration of high dose vitamin C of more than 1,000 mg was not associated with the length of hospital stay (p=0.677). Thus, high dose of vitamin C is not associated with the length of hospital stay for Covid-19 patients with comorbidities, such as hypertension, diabetes, and respiratory disease.http://journal.fk.unpad.ac.id/index.php/mkb/article/view/2582covid-19 patients with comorbidities, length of hospital stay, vitamin c
spellingShingle Budiyanti Wiboworini
Amelya Augusthina Ayusari
Risalina Myrtha
Dwi Rahayu
Widardo Widardo
Yulia Lanti
Amalina Shabrina
Joko Sudarsono
Sutartinah Sri Handayani
Graciella Angelica Lucas
Relationship between Vitamin C and Length of Hospital Stay for Covid-19 Patients with Comorbidities
Majalah Kedokteran Bandung
covid-19 patients with comorbidities, length of hospital stay, vitamin c
title Relationship between Vitamin C and Length of Hospital Stay for Covid-19 Patients with Comorbidities
title_full Relationship between Vitamin C and Length of Hospital Stay for Covid-19 Patients with Comorbidities
title_fullStr Relationship between Vitamin C and Length of Hospital Stay for Covid-19 Patients with Comorbidities
title_full_unstemmed Relationship between Vitamin C and Length of Hospital Stay for Covid-19 Patients with Comorbidities
title_short Relationship between Vitamin C and Length of Hospital Stay for Covid-19 Patients with Comorbidities
title_sort relationship between vitamin c and length of hospital stay for covid 19 patients with comorbidities
topic covid-19 patients with comorbidities, length of hospital stay, vitamin c
url http://journal.fk.unpad.ac.id/index.php/mkb/article/view/2582
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