The Effect of Niosomal System (Span 60-Cholesterol) on Diclofenac Sodium Preparation Characteristics and Diclofenac Sodium Preparation of Hydroxypropyl Cellulose Gel Base (HPC)

The Effect of Niosomal System (Span 60-Cholesterol) on Diclofenac Sodium Preparation Characteristics and Diclofenac Sodium Preparation of Hydroxypropyl Cellulose Gel Base (HPC)

Diclofenac sodium is a lipophilic drug. That characteristic makes it difficult to disperse well in hydrophilic gel base. The niosome with its vesicle system could overcome that low dispersibility. It affects penetration by reducing water loss in trans-epidermal layer and change lipid bilayer conform...

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Bibliographic Details
Main Authors: Adeltrudis Adelsa Danimayostu, Esti Hendradi, Tutiek Purwanti
Format: Article
Language:English
Published: University of Brawijaya 2017-05-01
Series:Research Journal of Life Science
Subjects:
diclofenac sodium
niosomal system (span 60-cholesterol)
hydroxypropyl cellulose
flux
permeability.
Online Access:http://rjls.ub.ac.id/index.php/rjls/article/view/121

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