Plasma Membrane Repair Is Regulated Extracellularly by Proteases Released from Lysosomes.
Eukaryotic cells rapidly repair wounds on their plasma membrane. Resealing is Ca(2+)-dependent, and involves exocytosis of lysosomes followed by massive endocytosis. Extracellular activity of the lysosomal enzyme acid sphingomyelinase was previously shown to promote endocytosis and wound removal. Ho...
Main Authors: | Thiago Castro-Gomes, Matthias Corrotte, Christina Tam, Norma W Andrews |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4814109?pdf=render |
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