Polyphenols—Gut Microbiota Interrelationship: A Transition to a New Generation of Prebiotics
The present review summarizes the studies carried out on this topic in the last five years. According to the new definitions, among all the compounds included in the group of prebiotics, polyphenols are probably the most important secondary metabolites produced by the plant kingdom. Many of these ty...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/1/137 |
| _version_ | 1797497974883876864 |
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| author | Diana Plamada Dan Cristian Vodnar |
| author_facet | Diana Plamada Dan Cristian Vodnar |
| author_sort | Diana Plamada |
| collection | DOAJ |
| description | The present review summarizes the studies carried out on this topic in the last five years. According to the new definitions, among all the compounds included in the group of prebiotics, polyphenols are probably the most important secondary metabolites produced by the plant kingdom. Many of these types of polyphenols have low bioavailability, therefore reaching the colon in unaltered form. Once in the colon, these compounds interact with the intestinal microbes bidirectionally by modulating them and, consequently, releasing metabolites. Despite much research on various metabolites, little is known about the chemistry of the metabolic routes used by different bacteria species. In this context, this review aims to investigate the prebiotic effect of polyphenols in preclinical and clinical studies, highlighting that the consumption of polyphenols leads to an increase in beneficial bacteria, as well as an increase in the production of valuable metabolites. In conclusion, there is much evidence in preclinical studies supporting the prebiotic effect of polyphenols, but further clinical studies are needed to investigate this effect in humans. |
| first_indexed | 2024-03-10T03:26:49Z |
| format | Article |
| id | doaj.art-3e445f4c0cec481dad97b53e6b345d3c |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T03:26:49Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-3e445f4c0cec481dad97b53e6b345d3c2023-11-23T12:04:46ZengMDPI AGNutrients2072-66432021-12-0114113710.3390/nu14010137Polyphenols—Gut Microbiota Interrelationship: A Transition to a New Generation of PrebioticsDiana Plamada0Dan Cristian Vodnar1Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, Calea Mănăștur 3-5, 400372 Cluj-Napoca, RomaniaFaculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, Calea Mănăștur 3-5, 400372 Cluj-Napoca, RomaniaThe present review summarizes the studies carried out on this topic in the last five years. According to the new definitions, among all the compounds included in the group of prebiotics, polyphenols are probably the most important secondary metabolites produced by the plant kingdom. Many of these types of polyphenols have low bioavailability, therefore reaching the colon in unaltered form. Once in the colon, these compounds interact with the intestinal microbes bidirectionally by modulating them and, consequently, releasing metabolites. Despite much research on various metabolites, little is known about the chemistry of the metabolic routes used by different bacteria species. In this context, this review aims to investigate the prebiotic effect of polyphenols in preclinical and clinical studies, highlighting that the consumption of polyphenols leads to an increase in beneficial bacteria, as well as an increase in the production of valuable metabolites. In conclusion, there is much evidence in preclinical studies supporting the prebiotic effect of polyphenols, but further clinical studies are needed to investigate this effect in humans.https://www.mdpi.com/2072-6643/14/1/137polyphenolsprebioticsgut microbiotabioactive compoundsbacteria |
| spellingShingle | Diana Plamada Dan Cristian Vodnar Polyphenols—Gut Microbiota Interrelationship: A Transition to a New Generation of Prebiotics Nutrients polyphenols prebiotics gut microbiota bioactive compounds bacteria |
| title | Polyphenols—Gut Microbiota Interrelationship: A Transition to a New Generation of Prebiotics |
| title_full | Polyphenols—Gut Microbiota Interrelationship: A Transition to a New Generation of Prebiotics |
| title_fullStr | Polyphenols—Gut Microbiota Interrelationship: A Transition to a New Generation of Prebiotics |
| title_full_unstemmed | Polyphenols—Gut Microbiota Interrelationship: A Transition to a New Generation of Prebiotics |
| title_short | Polyphenols—Gut Microbiota Interrelationship: A Transition to a New Generation of Prebiotics |
| title_sort | polyphenols gut microbiota interrelationship a transition to a new generation of prebiotics |
| topic | polyphenols prebiotics gut microbiota bioactive compounds bacteria |
| url | https://www.mdpi.com/2072-6643/14/1/137 |
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