Recurrent Respiratory Papillomatosis: an Extensive Review
Recurrent respiratory papillomatosis (RRP) is characterized by the recurrence of benign tumors (papillomata) in the aero digestive tract caused by Human Papilloma Virus. The burden for the patient and the society is non negligible, due to the high frequency of repetitive surgeries. The disease fo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2012-07-01
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| Series: | International Journal of Hematology-Oncology and Stem Cell Research |
| Subjects: | |
| Online Access: | http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/312/347 |
| _version_ | 1797726289004593152 |
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| author | Angelou Valerie Kalodimou E. Vasiliki |
| author_facet | Angelou Valerie Kalodimou E. Vasiliki |
| author_sort | Angelou Valerie |
| collection | DOAJ |
| description | Recurrent respiratory papillomatosis (RRP) is characterized by the recurrence of benign tumors (papillomata) in the aero digestive tract caused by Human Papilloma Virus. The burden for the patient and the society is non negligible, due to the high frequency of repetitive surgeries. The disease follows a bimodal age distribution. Usually the very first manifestation is hoarseness or voice changes but if negligee it can cause airway obstruction resulting in respiratorystridor or acute respiratory distress The treatment is challenging, includes surgery (mostly CO2 laser) and adjuvant medical therapy is almost always required (Cidofovir, interferon a, and others). The risk of malignant transformation is not negligent. Advances in immunology will lead us to understand the biology of HPV and will permit successful therapies. Prophylactic HPV vaccines are a promising area of research concerning RRP |
| first_indexed | 2024-03-12T10:43:27Z |
| format | Article |
| id | doaj.art-3e47e4be28404271bc437b15706670f6 |
| institution | Directory Open Access Journal |
| issn | 2008-3009 2008-2207 |
| language | English |
| last_indexed | 2024-03-12T10:43:27Z |
| publishDate | 2012-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | International Journal of Hematology-Oncology and Stem Cell Research |
| spelling | doaj.art-3e47e4be28404271bc437b15706670f62023-09-02T07:55:11ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-30092008-22072012-07-01633241Recurrent Respiratory Papillomatosis: an Extensive ReviewAngelou ValerieKalodimou E. VasilikiRecurrent respiratory papillomatosis (RRP) is characterized by the recurrence of benign tumors (papillomata) in the aero digestive tract caused by Human Papilloma Virus. The burden for the patient and the society is non negligible, due to the high frequency of repetitive surgeries. The disease follows a bimodal age distribution. Usually the very first manifestation is hoarseness or voice changes but if negligee it can cause airway obstruction resulting in respiratorystridor or acute respiratory distress The treatment is challenging, includes surgery (mostly CO2 laser) and adjuvant medical therapy is almost always required (Cidofovir, interferon a, and others). The risk of malignant transformation is not negligent. Advances in immunology will lead us to understand the biology of HPV and will permit successful therapies. Prophylactic HPV vaccines are a promising area of research concerning RRPhttp://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/312/347Human Papilloma VirusLaryngealCO2 LaserCidofovirTreatment |
| spellingShingle | Angelou Valerie Kalodimou E. Vasiliki Recurrent Respiratory Papillomatosis: an Extensive Review International Journal of Hematology-Oncology and Stem Cell Research Human Papilloma Virus Laryngeal CO2 Laser Cidofovir Treatment |
| title | Recurrent Respiratory Papillomatosis: an Extensive Review |
| title_full | Recurrent Respiratory Papillomatosis: an Extensive Review |
| title_fullStr | Recurrent Respiratory Papillomatosis: an Extensive Review |
| title_full_unstemmed | Recurrent Respiratory Papillomatosis: an Extensive Review |
| title_short | Recurrent Respiratory Papillomatosis: an Extensive Review |
| title_sort | recurrent respiratory papillomatosis an extensive review |
| topic | Human Papilloma Virus Laryngeal CO2 Laser Cidofovir Treatment |
| url | http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/312/347 |
| work_keys_str_mv | AT angelouvalerie recurrentrespiratorypapillomatosisanextensivereview AT kalodimouevasiliki recurrentrespiratorypapillomatosisanextensivereview |